The immune checkpoint pathway consisting of the cell membrane-bound molecule
programmed death protein 1 (PD-1) and its ligand PD-L1 has been found to mediate …

Programmed cell death protein-1 (PD-1) is a checkpoint receptor expressed on the surface
of various immune cells. PD-L1, the natural receptor for PD-1, is mainly expressed in tumor …

Simple Summary The interaction of programmed cell death ligand-1 (PDL1) with its receptor
PD1 inhibits T-cell responses. Blockade of this interaction with monoclonal antibodies leads …

Although targeting programmed death 1/programmed death ligand 1 (PD-1/PD-L1) has
achieved durable responses and disease remission in patients with certain cancers …

The prognostic role of soluble PD-L1 (sPD-L1) and exosomal PD-L1 (exoPD-L1) in patients
with gastric cancer (GC) receiving systemic chemotherapy remains unelucidated. Thus, we …

Simple Summary The search for non-invasive biomarkers is a hot topic in modern oncology,
since a tissue biopsy has significant limitations in terms of cost and invasiveness. The …

Background Circulating soluble programmed death ligand 1 (sPD-L1) can negatively
regulate T-cell function and serve as a prognostic or predictive marker in a variety of …

In recent years, immune checkpoint inhibitors (ICIs) have emerged as a transformative
approach in treating advanced hepatocellular carcinoma (HCC). Despite their success …

Cancer is a gravely important health issue all over the world and has been spreading fast. In
recent years immune checkpoint treatment options have been used extensively as a primary …

One of the mechanisms by which tumor cells can evade the immune system is over
activation of the programmed cell death protein-1 (PD-1)/programmed death-ligand 1 (PD …