Autoimmune hepatitis (AIH) is a rare disease of unclear etiology characterized by loss of self‐
tolerance that can lead to liver injury, cirrhosis, and acute liver failure. First‐line treatment …

Autoimmune hepatitis (AIH) is a rare disease of unclear etiology characterized by loss of self‐
tolerance that can lead to liver injury, cirrhosis, and acute liver failure. First‐line treatment …

Human corneal transplantation (keratoplasty) is typically considered to have superior short-
and long-term outcomes and lower requirement for immunosuppression compared to solid …

Progress in renal transplantation requires improved understanding and assessment of
rejection and injury. Study of the relationship between gene expression and clinical …

Noninvasive biomarkers are needed to monitor stable patients after kidney transplant (KT),
because subclinical acute rejection (subAR), currently detectable only with surveillance …

Background Immunosuppression nonadherence increases the risk for kidney transplant loss
after transplantation. Wireless-enabled pill bottles have created the opportunity to monitor …

Results For diagnosing subclinical rejection, the gene expression profile demonstrated a
negative predictive value of 82%, a positive predictive value of 47%, a balanced accuracy of …

Background Sepsis involves aberrant immune responses to infection, but the exact nature of
this immune dysfunction remains poorly defined. Bacterial endotoxins like …

Background Antibody-mediated rejection, a leading cause of renal allograft graft failure, is
diagnosed by histological assessment of invasive allograft biopsies. Accurate non-invasive …

The immune system plays a key role in health maintenance and pathogenesis of a wide
range of diseases. Leukocytes that are present in the blood convey valuable information …