Emerging technologies for molecular diagnosis of sepsis

M Sinha, J Jupe, H Mack, TP Coleman… - Clinical microbiology …, 2018 - Am Soc Microbiol
Rapid and accurate profiling of infection-causing pathogens remains a significant challenge
in modern health care. Despite advances in molecular diagnostic techniques, blood culture …

Practical guidance for clinical microbiology laboratories: a comprehensive update on the problem of blood culture contamination and a discussion of methods for …

GV Doern, KC Carroll, DJ Diekema… - Clinical microbiology …, 2019 - Am Soc Microbiol
In this review, we present a comprehensive discussion of matters related to the problem of
blood culture contamination. Issues addressed include the scope and magnitude of the …

[HTML][HTML] Contaminants in blood cultures: importance, implications, interpretation and prevention

S Dargère, H Cormier, R Verdon - Clinical Microbiology and Infection, 2018 - Elsevier
Background Despite the development of new microbiologic technologies, blood cultures
(BCs) remain the first-line tool for the diagnosis of bloodstream infections. Their diagnostic …

[HTML][HTML] Best practices of blood cultures in low-and middle-income countries

S Ombelet, B Barbé, D Affolabi, JB Ronat… - Frontiers in …, 2019 - frontiersin.org
Bloodstream infections (BSI) have a substantial impact on morbidity and mortality worldwide.
Despite scarcity of data from many low-and middle-income countries (LMICs), there is …

Multidisciplinary team review of best practices for collection and handling of blood cultures to determine effective interventions for increasing the yield of true-positive …

RA Garcia, ED Spitzer, J Beaudry, C Beck… - American journal of …, 2015 - Elsevier
Background A literature search was conducted using keywords for articles published in
English from January 1990 to March 2015. Using criteria related to blood culture collection …

[HTML][HTML] Enhanced performance of next-generation sequencing diagnostics compared with standard of care microbiological diagnostics in patients suffering from …

S Grumaz, C Grumaz, Y Vainshtein… - Critical care …, 2019 - journals.lww.com
Objectives: Culture-based diagnostics represent the standard of care in septic patients, but
are highly insensitive and in many cases unspecific. We recently demonstrated the general …

[图书][B] Molecular detection of human bacterial pathogens

D Liu - 2011 - books.google.com
As more original molecular protocols and subsequent modifications are described in the
literature, it has become difficult for those not directly involved in the development of these …

Reduction in blood culture contamination through use of initial specimen diversion device

ME Rupp, RJ Cavalieri, C Marolf… - Clinical Infectious …, 2017 - academic.oup.com
Background. Blood culture contamination is a clinically significant problem that results in
patient harm and excess cost. Methods. In a prospective, controlled trial at an academic …

Timing of appropriate empirical antimicrobial administration and outcome of adults with community-onset bacteremia

CC Lee, CH Lee, MY Hong, HJ Tang, WC Ko - Critical Care, 2017 - Springer
Background Early administration of appropriate antimicrobials has been correlated with a
better prognosis in patients with bacteremia, but the optimum timing of early antibiotic …

Bacillus cereus bacteremia outbreak due to contaminated hospital linens

T Sasahara, S Hayashi, Y Morisawa… - European journal of …, 2011 - Springer
We describe an outbreak of Bacillus cereus bacteremia that occurred at Jichi Medical
University Hospital in 2006. This study aimed to identify the source of this outbreak and to …