Curcumin formulations for better bioavailability: what we learned from clinical trials thus far?

M Hegde, S Girisa, B BharathwajChetty, R Vishwa… - ACS …, 2023 - ACS Publications
Curcumin has been credited with a wide spectrum of pharmacological properties for the
prevention and treatment of several chronic diseases such as arthritis, autoimmune …

[HTML][HTML] Effectiveness of curcumin on outcomes of hospitalized COVID-19 patients: A systematic review of clinical trials

A Vahedian-Azimi, M Abbasifard, F Rahimi-Bashar… - Nutrients, 2022 - mdpi.com
Despite the ongoing vaccination efforts, there is still an urgent need for safe and effective
treatments to help curb the debilitating effects of COVID-19 disease. This systematic review …

[HTML][HTML] Curcumin and type 2 diabetes mellitus: prevention and treatment

F Pivari, A Mingione, C Brasacchio, L Soldati - Nutrients, 2019 - mdpi.com
Type 2 diabetes mellitus (T2DM) is an ensemble of metabolic diseases that has reached
pandemic dimensions all over the world. The multifactorial nature of the pathology makes …

[HTML][HTML] Molecular and pharmacological aspects of piperine as a potential molecule for disease prevention and management: evidence from clinical trials

AK Tripathi, AK Ray, SK Mishra - Beni-Suef university journal of basic and …, 2022 - Springer
Background Piperine is a type of amide alkaloid that exhibits pleiotropic properties like
antioxidant, anticancer, anti-inflammatory, antihypertensive, hepatoprotective …

Role of turmeric and curcumin in prevention and treatment of chronic diseases: Lessons learned from clinical trials

AB Kunnumakkara, M Hegde, D Parama… - ACS Pharmacology & …, 2023 - ACS Publications
Turmeric (Curcuma longa) has been used for thousands of years for the prevention and
treatment of various chronic diseases. Curcumin is just one of> 200 ingredients in turmeric …

Mechanisms of apoptosis modulation by curcumin: Implications for cancer therapy

K Mortezaee, E Salehi… - Journal of cellular …, 2019 - Wiley Online Library
Cancer incidences are growing and cause millions of deaths worldwide. Cancer therapy is
one of the most important challenges in medicine. Improving therapeutic outcomes from …

Curcumin‐piperine co‐supplementation and human health: a comprehensive review of preclinical and clinical studies

H Heidari, M Bagherniya, M Majeed… - Phytotherapy …, 2023 - Wiley Online Library
Curcumin is extracted from the rhizomes Curcuma longa L. It is known for its anti‐
inflammatory and anti‐oxidant activities. Despite its safety and potential for use against …

The protective role of curcumin in myocardial ischemia–reperfusion injury

A Mokhtari‐Zaer, N Marefati, SL Atkin… - Journal of cellular …, 2019 - Wiley Online Library
Coronary artery disease (CAD) is a well‐known pathological condition that is characterized
by high morbidity and mortality. The main pathological manifestation of CAD is myocardial …

Antioxidant and anti-inflammatory effects of curcumin/turmeric supplementation in adults: A GRADE-assessed systematic review and dose–response meta-analysis of …

MJ Dehzad, H Ghalandari, M Nouri, M Askarpour - Cytokine, 2023 - Elsevier
Turmeric and its prominent bioactive compound, curcumin, have been the subject of many
investigations with regard to their impact on inflammatory and oxidative balance in the body …

A review of the molecular mechanisms of hyperglycemia‐induced free radical generation leading to oxidative stress

H Yaribeygi, SL Atkin… - Journal of cellular …, 2019 - Wiley Online Library
The prevalence of diabetes is growing worldwide with an increasing morbidity and mortality
associated with the development of diabetes complications. Free radical production is a …