Specific primer design for the polymerase chain reaction

LY Chuang, YH Cheng, CH Yang - Biotechnology letters, 2013 - Springer
The design of primers has a major impact on the success of PCR in relation to the specificity
and yield of the amplified product. Here, we introduce the applications of PCR as well as the …

[HTML][HTML] New design of variable structure control based on lightning search algorithm for nuclear reactor power system considering load-following operation

M Elsisi, H Abdelfattah - Nuclear Engineering and Technology, 2020 - Elsevier
Reactor control is a standout amongst the most vital issues in the nuclear power plant. In this
paper, the optimal design of variable structure controller (VSC) based on the lightning …

Naturally selecting solutions: the use of genetic algorithms in bioinformatics

T Manning, RD Sleator, P Walsh - Bioengineered, 2013 - Taylor & Francis
For decades, computer scientists have looked to nature for biologically inspired solutions to
computational problems; ranging from robotic control to scheduling optimization …

Evaluation of breast cancer susceptibility using improved genetic algorithms to generate genotype SNP barcodes

CH Yang, YD Lin, LY Chuang… - IEEE/ACM transactions …, 2013 - ieeexplore.ieee.org
Genetic association is a challenging task for the identification and characterization of genes
that increase the susceptibility to common complex multifactorial diseases. To fully execute …

[HTML][HTML] LociScan, a tool for screening genetic marker combinations for plant variety discrimination

Y Yang, H Tian, H Yi, Z Shi, L Wang, Y Fan, F Wang… - The Crop Journal, 2024 - Elsevier
To reduce the cost and increase the efficiency of plant genetic marker fingerprinting for
variety discrimination, it is desirable to identify the optimal marker combinations. We …

Multiobjective optimization-driven primer design mechanism: towards user-specified parameters of PCR primer

CH Yang, YH Cheng, EC Yang… - Briefings in …, 2022 - academic.oup.com
Primers are critical for polymerase chain reaction (PCR) and influence PCR experimental
outcomes. Designing numerous combinations of forward and reverse primers involves …

[PDF][PDF] Genetic algorithm combined with a local search method for identifying susceptibility genes

CH Yang, SH Moi, YD Lin, LY Chuang - Journal of Artificial …, 2016 - sciendo.com
Detecting genetic association models between single nucleotide polymorphisms (SNPs) in
various disease-related genes can help to understand susceptibility to disease. Statistical …

A novel teaching-learning-based optimization for improved mutagenic primer design in mismatch PCR-RFLP SNP genotyping

YH Cheng - IEEE/ACM Transactions on Computational Biology …, 2015 - ieeexplore.ieee.org
Many single nucleotide polymorphisms (SNPs) for complex genetic diseases are genotyped
by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in …

[PDF][PDF] Дизайн праймеров для полимеразной цепной реакции (краткий обзор компьютерных программ и баз данных)

ДА Чемерис, ОЮ Кирьянова, ИМ Губайдуллин… - Биомика, 2016 - biomicsj.ru
Резюме За три десятилетия своего существования полимеразная цепная реакция
(ПЦР) стала практически вездесущей. Приблизительно в каждой восьмой работе, где …

Estimation of teaching-learning-based optimization primer design using regression analysis for different melting temperature calculations

YH Cheng - IEEE transactions on nanobioscience, 2014 - ieeexplore.ieee.org
Primers plays important role in polymerase chain reaction (PCR) experiments, thus it is
necessary to select characteristic primers. Unfortunately, manual primer design manners are …