Abstract
Within this chapter we introduce the basic PLINK functions for reading in data, applying quality control, and running association analyses. Three worked examples are provided to illustrate: data management and assessment of population substructure, association analysis of a quantitative trait, and qualitative or case–control association analyses.
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Reference
Purcell S et al (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81(3):559–575
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Rentería, M.E., Cortes, A., Medland, S.E. (2013). Using PLINK for Genome-Wide Association Studies (GWAS) and Data Analysis. In: Gondro, C., van der Werf, J., Hayes, B. (eds) Genome-Wide Association Studies and Genomic Prediction. Methods in Molecular Biology, vol 1019. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-447-0_8
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DOI: https://doi.org/10.1007/978-1-62703-447-0_8
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Publisher Name: Humana Press, Totowa, NJ
Print ISBN: 978-1-62703-446-3
Online ISBN: 978-1-62703-447-0
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