Cellular respiration: the nexus of stress, condition, and ornamentation

GE Hill - Integrative and comparative biology, 2014 - academic.oup.com
A fundamental hypothesis for the evolution and maintenance of ornamental traits is that
ornaments convey information to choosing females about the quality of prospective mates. A …

Mitonuclear genomics and aging

JC Reynolds, CP Bwiza, C Lee - Human genetics, 2020 - Springer
Our cells operate based on two distinct genomes that are enclosed in the nucleus and
mitochondria. The mitochondrial genome presumably originates from endosymbiotic …

Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease

JC Fitzgerald, A Zimprich, DA Carvajal Berrio… - Brain, 2017 - academic.oup.com
The mitochondrial proteins TRAP1 and HTRA2 have previously been shown to be
phosphorylated in the presence of the Parkinson's disease kinase PINK1 but the …

A review and assessment of the shared-pathway hypothesis for the maintenance of signal honesty in red ketocarotenoid-based coloration

MJ Powers, GE Hill - Integrative and comparative biology, 2021 - academic.oup.com
For decades, scientists have noted connections between individual condition and
carotenoid-based coloration in terrestrial and aquatic animals. Organisms that produce more …

MOTS‐c: a mitochondrial‐encoded regulator of the nucleus

BA Benayoun, C Lee - BioEssays, 2019 - Wiley Online Library
Mitochondria are increasingly being recognized as information hubs that sense cellular
changes and transmit messages to other cellular components, such as the nucleus, the …

Linking mitochondrial dynamics to mitochondrial protein quality control

S Haroon, M Vermulst - Current opinion in genetics & development, 2016 - Elsevier
Over the last decade, countless discoveries have been made that have expanded our
knowledge of mitochondrial biology, and more often than not, these discoveries provided …

FoxO1 localizes to mitochondria of adipose tissue and is affected by nutrient stress

D Lettieri-Barbato, L Ioannilli, K Aquilano, F Ciccarone… - Metabolism, 2019 - Elsevier
Objective Mitochondria play pivotal roles in orchestrating signaling pathways in order to
guarantee metabolic homeostasis under different stimuli. It has been demonstrated that the …

Heme oxygenase-1 protects against endotoxin-induced acute lung injury depends on NAD+-mediated mitonuclear communication through PGC1α/PPARγ signaling …

S He, J Shi, W Liu, S Du, Y Zhang, L Gong, S Dong… - Inflammation …, 2022 - Springer
Endotoxin-induced acute lung injury (ALI) is a challenging life-threatening disease for which
no specific therapy exists. Mitochondrial dysfunction is corroborated as hallmarks in sepsis …

Biomolecular bases of the senescence process and cancer. A new approach to oncological treatment linked to ageing

I Badiola, F Santaolalla, P Garcia-Gallastegui… - Ageing Research …, 2015 - Elsevier
Human ageing is associated with a gradual decline in the physiological functions of the
body at multiple levels and it is a key risk factor for many diseases, including cancer. Ageing …

Cell-nonautonomous mechanisms underlying cellular and organismal aging

Y Medkour, V Svistkova, VI Titorenko - … review of cell and molecular biology, 2016 - Elsevier
Cell-autonomous mechanisms underlying cellular and organismal aging in evolutionarily
distant eukaryotes have been established; these mechanisms regulate longevity-defining …