Viscoelasticity in natural tissues and engineered scaffolds for tissue reconstruction

D Huang, Y Huang, Y Xiao, X Yang, H Lin, G Feng… - Acta biomaterialia, 2019 - Elsevier
Viscoelasticity of living tissues plays a critical role in tissue homeostasis and regeneration,
and its implication in disease development and progression is being recognized recently. In …

Prospects of chitosan-based scaffolds for growth factor release in tissue engineering

PR Sivashankari, M Prabaharan - International journal of biological …, 2016 - Elsevier
Tissue engineering is concerned about the rejuvenation and restoration of diseased and
damages tissues/organs using man-made scaffolds that mimic the native environment of the …

Diabetic wound regeneration using peptide-modified hydrogels to target re-epithelialization

Y Xiao, LA Reis, N Feric, EJ Knee… - Proceedings of the …, 2016 - National Acad Sciences
There is a clinical need for new, more effective treatments for chronic wounds in diabetic
patients. Lack of epithelial cell migration is a hallmark of nonhealing wounds, and diabetes …

Cellulose nanocrystal reinforced collagen-based nanocomposite hydrogel with self-healing and stress-relaxation properties for cell delivery

S Zhang, D Huang, H Lin, Y Xiao, X Zhang - Biomacromolecules, 2020 - ACS Publications
While injectable in situ cross-linking collagen hydrogels offer great potential for applying
stem cell therapy to regenerate articular cartilage via minimally invasive procedures, the …

[HTML][HTML] based cell culture platform and its emerging biomedical applications

K Ng, B Gao, KW Yong, Y Li, M Shi, X Zhao, Z Li… - Materials Today, 2017 - Elsevier
Paper has recently attracted increasing attention as a substrate for various biomedical
applications. By modifying its physical and chemical properties, paper can be used as an …

Application of an instructive hydrogel accelerates re-epithelialization of xenografted human skin wounds

HD Sparks, S Mandla, K Vizely, N Rosin, M Radisic… - Scientific Reports, 2022 - nature.com
Poor quality (eg. excessive scarring) or delayed closure of skin wounds can have profound
physical and pyschosocial effects on patients as well as pose an enormous economic …

Wound dressings: curbing inflammation in chronic wound healing

DV Verdolino, HA Thomason… - Emerging topics in life …, 2021 - portlandpress.com
Chronic wounds represent an economic burden to healthcare systems worldwide and a
societal burden to patients, deeply impacting their quality of life. The incidence of recalcitrant …

Investigation of angiogenesis in bioactive 3-dimensional poly (d, l-lactide-co-glycolide)/nano-hydroxyapatite scaffolds by in vivo multiphoton microscopy in murine …

J Li, Q Xu, B Teng, C Yu, L Song, Y Lai, J Zhang… - Acta biomaterialia, 2016 - Elsevier
Reconstruction of critical size bone defects remains a major clinical challenge because of
poor bone regeneration, which is usually due to poor angiogenesis during repair …

Biodegradable polymers: medical applications

KR Kunduru, A Basu, AJ Domb - Encyclopedia of polymer …, 2002 - Wiley Online Library
Biodegradable polymers are the “green materials” of the future. They break down into
smaller chemical fragments and are finally eliminated from the body. Biodegradable …

Angiopoietin-1 derived peptide hydrogel promotes molecular hallmarks of regeneration and wound healing in dermal fibroblasts

K Vizely, KT Wagner, S Mandla, D Gustafson, JE Fish… - Iscience, 2023 - cell.com
By providing an ideal environment for healing, biomaterials can be designed to facilitate and
encourage wound regeneration. As the wound healing process is complex, there needs to …