Recent advances in urea-and thiourea-containing compounds: focus on innovative approaches in medicinal chemistry and organic synthesis

R Ronchetti, G Moroni, A Carotti, A Gioiello… - RSC medicinal …, 2021 - pubs.rsc.org
Urea and thiourea represent privileged structures in medicinal chemistry. Indeed, these
moieties constitute a common framework of a variety of drugs and bioactive compounds …

Recent trends in chemistry, structure, and various applications of 1-acyl-3-substituted thioureas: a detailed review

U Zahra, A Saeed, TA Fattah, U Flörke, MF Erben - RSC advances, 2022 - pubs.rsc.org
The interest in acyl thioureas has continually been escalating owing to their extensive
applications in diverse fields, such as synthetic precursors of new heterocycles …

Recent advances in thiourea based colorimetric and fluorescent chemosensors for detection of anions and neutral analytes: a review

HM Al-Saidi, S Khan - Critical Reviews in Analytical Chemistry, 2024 - Taylor & Francis
Thioureas and their derivatives are organosulfur compounds having excellent biological and
non-biological applications. These compounds contain S-and N-, which are nucleophilic …

Novel adamantyl clubbed iminothiazolidinones as promising elastase inhibitors: design, synthesis, molecular docking, ADMET and DFT studies

A Ahmed, A Saeed, SA Ejaz, M Aziz, MZ Hashmi… - RSC …, 2022 - pubs.rsc.org
Porcine Pancreatic Elastase (PPE) is a serine protease that is homologous to trypsin and
chymotrypsin that are involved in various pathologies like inflammatory disease, Chronic …

Advances in the Synthesis and Applications of N-Heterocyclic Carbene Metal Complexes with a Focus on the Weak Base Route

T Scattolin, AA Logvinov, NV Tzouras, CSJ Cazin… - …, 2023 - ACS Publications
N-heterocyclic carbene (NHC) ligands have evolved from being simple lab curiosities to
tertiary phosphine mimics to finally take center stage as unique supporting ligands in …

Structural, conformational and therapeutic studies on new thiazole complexes: drug-likeness and MOE-simulation assessments

AM Abu-Dief, NM El-Metwaly, SO Alzahrani… - Research on Chemical …, 2021 - Springer
A series of new complexes derived from Pd (II), Cu (II) and Fe (III) ions reacted with thiazole
derivative (HL, CPTP) was prepared. Structures of all new compounds were characterized …

DFT, anticancer, antioxidant and molecular docking investigations of some ternary Ni (II) complexes with 2-[(E)-[4-(dimethylamino) phenyl] methyleneamino] phenol

RK Mohapatra, MM El-ajaily, FS Alassbaly, AK Sarangi… - Chemical Papers, 2021 - Springer
The biological activities of some ternary nickel complexes with a Schiff base obtained from 4-
dimethylaminobenzaldehyde and 2-aminophenol have been reported. The Schiff base (HL …

Medicinal chemistry of oxazines as promising agents in drug discovery

DS Zinad, A Mahal, RK Mohapatra… - Chemical biology & …, 2020 - Wiley Online Library
Oxazines have brought much synthetic interest due to their extensive biological activities.
These are the important category of heterocycles, which may be formally derived from …

Synthesis, structural investigations, XRD, DFT, anticancer and molecular docking study of a series of thiazole based Schiff base metal complexes

RK Al-Shemary, RK Mohapatra, M Kumar… - Journal of Molecular …, 2023 - Elsevier
A novel Schiff base (SB) ligand, abbreviated as HDMPM, resulted from the condensation of
2-amino-4-phenyl-5-methyl thiazole and 4-(diethylamino) salicyaldehyde, and its metal …

Exploring the utilization of Schiff base metal complexes in biological settings: A review

TR Arun, HP Kumar, S Kamalesu - Inorganic Chemistry Communications, 2024 - Elsevier
The present work explores the growing field of Schiff base metal complexes, highlighting
their increasing importance in biological contexts. Schiff base metal complexes …