Ecological validity of social interaction tests in rats and mice

K Kondrakiewicz, M Kostecki… - Genes, Brain and …, 2019 - Wiley Online Library
Different rat and mouse models are used in studies of social interactions. Simple behavioral
measures, which are commonly used in the laboratory, allow to perform relatively short …

The neural plasticity theory of depression: Assessing the roles of adult neurogenesis and PSA‐NCAM within the hippocampus

SR Wainwright, LAM Galea - Neural plasticity, 2013 - Wiley Online Library
Depression is a devastating and prevalent disease, with profound effects on neural structure
and function; however the etiology and neuropathology of depression remain poorly …

The type of stress matters: repeated injection and permanent social isolation stress in male mice have a differential effect on anxiety-and depressive-like behaviours …

A Du Preez, T Law, D Onorato, YM Lim, P Eiben… - Translational …, 2020 - nature.com
Chronic stress can alter the immune system, adult hippocampal neurogenesis and induce
anxiety-and depressive-like behaviour in rodents. However, previous studies have not …

Effects of single cage housing on stress, cognitive, and seizure parameters in the rat and mouse pilocarpine models of epilepsy

H Manouze, A Ghestem, V Poillerat, M Bennis… - Eneuro, 2019 - eneuro.org
Many experimental approaches require housing rodents in individual cages, including in
epilepsy research. However, rats and mice are social animals; and individual housing …

Parvalbumin interneuron in the ventral hippocampus functions as a discriminator in social memory

X Deng, L Gu, N Sui, J Guo… - Proceedings of the …, 2019 - National Acad Sciences
The ability to identify strange conspecifics in societies is supported by social memory, which
is vital for gregarious animals and humans. The function of hippocampal principal neurons …

Hippocampal BDNF in physiological conditions and social isolation

I Zaletel, D Filipović, N Puškaš - Reviews in the Neurosciences, 2017 - degruyter.com
Exposure of an organism to chronic psychosocial stress may affect brain-derived
neurotrophic factor (BDNF) expression that has been implicated in the etiology of psychiatric …

Different susceptibility of prefrontal cortex and hippocampus to oxidative stress following chronic social isolation stress

J Zlatković, N Todorović, M Bošković… - Molecular and cellular …, 2014 - Springer
Chronic oxidative stress plays an important role in depression. The aim of present study was
to examine the stress-induced changes in serum corticosterone (CORT) levels, cytosolic …

Fluoxetine ameliorates Alzheimer's disease progression and prevents the exacerbation of cardiovascular dysfunction of socially isolated depressed rats through …

K Abu-Elfotuh, AH Al-Najjar, AA Mohammed… - International …, 2022 - Elsevier
Depression is a risk factor for Alzheimer's (AD) and cardiovascular diseases (CVD).
Therefore, depression treatment restricts its deteriorating effects on mood, memory and CV …

The effect of acute crocin on behavioral changes and BDNF expression level in socially isolated rats

AK Kamaei, SF Hosseini, P Teimourparsaei… - Naunyn-Schmiedeberg's …, 2024 - Springer
Social isolation is a reliable method used for the induction of depression and psychiatric
disorders in rodents. It has been suggested that social isolation can lead to …

Review of major social determinants of health in schizophrenia-spectrum psychotic disorders: III. Biology

DV Jeste, D Malaspina, K Bagot, DM Barch… - Schizophrenia …, 2023 - academic.oup.com
Background Social determinants of health (SDoHs) are nonmedical factors that significantly
impact health and longevity. We found no published reviews on the biology of SDoHs in …