Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …

Open PHACTS is a public–private partnership between academia, publishers, small and
medium sized enterprises and pharmaceutical companies. The goal of the project is to …

Many scientists now manage the bulk of their bibliographic information electronically,
thereby organizing their publications and citation material from digital libraries. However, a …

Abstract The National Center for Biomedical Ontology is now in its seventh year. The goals
of this National Center for Biomedical Computing are to: create and maintain a repository of …

Over the past couple of decades, the explosion of densely interconnected data has
stimulated the research, development and adoption of graph database technologies. From …

Solute carriers (SLCs) are the largest family of transmembrane transporters in the human
genome with more than 400 members. Despite the fact that SLCs mediate critical biological …

Ontologies are now pervasive in biomedicine, where they serve as a means to standardize
terminology, to enable access to domain knowledge, to verify data consistency and to …

Background Ontologies are increasingly used to structure and semantically describe entities
of domains, such as genes and proteins in life sciences. Their increasing size and the high …

Software maintainers routinely have to deal with a multitude of artifacts, like source code or
documents, which often end up disconnected, due to their different representations and the …

Abstract Service-oriented architecture (SOA), workflow, the Semantic Web, and Grid
computing are key enabling information technologies in the development of increasingly …