Managing the immune microenvironment of osteosarcoma: the outlook for osteosarcoma treatment

H Tian, J Cao, B Li, EC Nice, H Mao, Y Zhang… - Bone Research, 2023 - nature.com
Osteosarcoma, with poor survival after metastasis, is considered the most common primary
bone cancer in adolescents. Notwithstanding the efforts of researchers, its five-year survival …

Reigniting hope in cancer treatment: the promise and pitfalls of IL-2 and IL-2R targeting strategies

S Muhammad, T Fan, Y Hai, Y Gao, J He - Molecular Cancer, 2023 - Springer
Abstract Interleukin-2 (IL-2) and its receptor (IL-2R) are essential in orchestrating immune
responses. Their function and expression in the tumor microenvironment make them …

Macrophage subsets and their role: co-relation with colony-stimulating factor-1 receptor and clinical relevance

S Yadav, A Priya, DR Borade, R Agrawal-Rajput - Immunologic Research, 2023 - Springer
Macrophages are one of the first innate immune cells to reach the site of infection or injury.
Diverse functions from the uptake of pathogen or antigen, its killing, and presentation, the …

[HTML][HTML] Propranolol reduces IFN-γ driven PD-L1 immunosuppression and improves anti-tumour immunity in ovarian cancer

M Falcinelli, G Al-Hity, S Baron, M Mampay… - Brain, Behavior, and …, 2023 - Elsevier
The immune system plays an important role in controlling epithelial ovarian cancer (EOC).
EOC is considered to be a “cold tumour,” a tumour that has not triggered a strong response …

Chlamydia trachomatis infection co-operatively enhances HPV E6-E7 oncogenes mediated tumorigenesis and immunosuppression

N Challagundla, J Chrisophe-Bourdon… - Microbial …, 2023 - Elsevier
Chlamydia trachomatis and human papilloma virus (HPV) are the two most common
sexually transmitted infections among women. HPV infection can increase the risk of cervical …

The tale of antibiotics beyond antimicrobials: Expanding horizons

S Yadav, D Shah, P Dalai, R Agrawal-Rajput - Cytokine, 2023 - Elsevier
Antibiotics had proved to be a godsend for mankind since their discovery. They were once
the magical solution to the vexing problem of infection-related deaths. German scientist Paul …

Cellular atlas of senescent lineages in radiation-or immunotherapy-induced lung injury by single-cell RNA-sequencing analysis

F Wu, Z Zhang, M Wang, Y Ma, V Verma, C Xiao… - International Journal of …, 2023 - Elsevier
Purpose Although the combination of immunotherapy and radiation therapy to treat various
malignancies is rapidly expanding, concerns regarding increased pulmonary toxicities …

Host Lipid Manipulation by Intracellular Bacteria: Moonlighting for Immune Evasion

N Challagundla, D Phadnis, A Gupta… - The Journal of …, 2023 - Springer
Lipids are complex organic molecules that fulfill energy demands and sometimes act as
signaling molecules. They are mostly found in membranes, thus playing an important role in …

Natural phytochemicals reverting M2 to M1 macrophages: A novel alternative Leishmaniasis therapy

A Mohanty, V Vekariya, S Yadav… - Microbial Pathogenesis, 2025 - Elsevier
Introduction Leishmaniasis is a tropical parasitic disease caused by the protozoan
Leishmania which remains a significant global health concern with diverse clinical …

[PDF][PDF] Serum of Interferon Lambda-1 level as a protein biomarker for the diagnosis of COVID-19 severity

SA Abbas, HA Ali, RA Ali, MS Mashkur… - Current Issues in …, 2024 - sciendo.com
The novel coronavirus was given the name SARS-CoV-2 due to its 80% similarity to the
severe acute respiratory syndrome coronavirus-1 (SARS-CoV-1), which caused acute …