Chitosan and its derivatives for ocular delivery formulations: Recent advances and developments

A Zamboulis, S Nanaki, G Michailidou, I Koumentakou… - Polymers, 2020 - mdpi.com
Chitosan (CS) is a hemi-synthetic cationic linear polysaccharide produced by the
deacetylation of chitin. CS is non-toxic, highly biocompatible, and biodegradable, and it has …

A meticulous overview on drying-based (spray-, freeze-, and spray-freeze) particle engineering approaches for pharmaceutical technologies

S Pardeshi, M More, P Patil, C Pardeshi… - Drying …, 2021 - Taylor & Francis
Drying is an indispensable operation in the preparation of pharmaceutical powders and
always remained one of the energetic tasks in the pharmaceutical industry. Improving the …

3D-Printed chitosan-based hydrogels loaded with levofloxacin for tissue engineering applications

I Koumentakou, MJ Noordam, A Michopoulou… - …, 2023 - ACS Publications
Herein, we demonstrate the feasibility of a three-dimensional printed chitosan (CS)–poly
(vinyl alcohol)(PVA)–gelatin (Gel) hydrogel incorporating the antimicrobial drug levofloxacin …

An enzyme-particle hybrid ink for one step screen-printing and long-term metabolism monitoring

C Wang, X Zhang, Y Liu, J Li, L Zhu, Y Lu, X Guo… - Analytica Chimica …, 2022 - Elsevier
Targeting the long-term monitoring of biological carbohydrate metabolism, we developed a
one-step screen-printing method to fabricate electrochemical sensors using an enzyme …

Cross-linked chitosan microparticles preparation by modified three fluid nozzle spray drying approach

MG Antoniraj, MM Leena, JA Moses… - International journal of …, 2020 - Elsevier
Owing to chitosan's incredible biocompatibility and biodegradability, bioactive molecules
loaded delivery systems based on this polymer have been widely studied for improved …

Study of the influence of the excipients used for the synthesis of microspheres loaded with quercetin: Their characterization and antimicrobial activity

OD Frent, DM Duda-Seiman, LG Vicas, N Duteanu… - Coatings, 2023 - mdpi.com
The aim of this study was to determine the potential pharmaceutical applications of quercetin—
a natural flavonoid compound with a polyphenolic structure—following its encapsulation in …

Single step nanospray drying preparation technique of gabapentin-loaded nanoparticles-mediated brain delivery for effective treatment of PTZ-induced seizures

AH Salama, AAA Salama, M Elhabak - International Journal of …, 2021 - Elsevier
In the present study, gabapentin (GBP)-loaded chitosan nanosized particles were fabricated
applying the nanospray drying technique. Different preparation parameters (spray mesh …

Nose-to-brain delivery of galantamine loaded nanospray dried polyacrylic acid/taurodeoxycholate mixed matrix as a protective therapy in lipopolysaccharide-induced …

M Elhabak, AAA Salama, AH Salama - International Journal of …, 2023 - Elsevier
One of the promising drug delivery approaches is performed by nanosizing the administered
drug product using the nanospray drying technique. In this study, a combination of several …

Controlled drug release and antibacterial properties of levofloxacin-loaded silk/chitosan green composite for wound dressing

Z Suhail, H Shoukat, N Sanbhal, N Chowdhry… - Biomedical Materials & …, 2023 - Springer
Antibacterial wound dressings have great importance to reduce wound infections caused by
bacteria. In this research work, levofloxacin-loaded silk fibroin and chitosan composite …

[HTML][HTML] Biodegradable microspheres come into sight: A promising biomaterial for delivering drug to the posterior segment of the eyeball

R Xue, H Wu, S Li, N Pu, D Wei, N Zhao, Y Cui, H Li… - Materials Today Bio, 2024 - Elsevier
Posterior segment disease acts as a major cause of irreversible visual impairments.
Successful treatment of posterior segment disease requires the efficient delivery of …