Type 2 diabetes (T2D) is a metabolic disease with impact on brain function through
mechanisms that include glucose toxicity, vascular damage and blood–brain barrier (BBB) …

Environmental enrichment (EE) is a process of brain stimulation by modifying the
surroundings, for example, by changing the sensory, social, or physical conditions. Rodents …

Nonalcoholic steatohepatitis (NASH) is one of the most prevalent diseases globally. A high-
fat, high-cholesterol (HFHC) diet leads to an early NASH model. It has been suggested that …

Metabolic syndrome (MetS) is defined by the concurrence of different metabolic conditions:
obesity, hypertension, dyslipidemia, and hyperglycemia. Its incidence has been increasingly …

Background: Physical activity is associated with improved brain health and cognition in
humans. However, the validity, range, and quality of evidence for the beneficial outcomes …

Obesity represents a risk factor for metabolic syndrome and cardiovascular and psychiatric
disorders. Excessive caloric intake, particularly in dietary fats, is an environmental factor that …

Hypercholesterolemia has been linked to neurodegenerative disease development.
Previously others and we demonstrated that high levels of plasma cholesterol-induced …

Simple Summary Type 2 diabetes can lead to catastrophic complications, including
neurodegeneration and memory impairment. Therefore, it is essential to identify effective …

Semi-synthetic and grain-based diets are common rodent diets for biomedical research.
Both diet types are considered nutritionally adequate to support breeding, growth, and long …

Convincing evidence shows that stress is associated with the development and course of
psychiatric and metabolic disorders. The hypothalamic-pituitary-adrenal (HPA) axis …