[HTML][HTML] The case for early identification and intervention of chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) …

MG Shlipak, SL Tummalapalli, LE Boulware… - Kidney international, 2021 - Elsevier
Chronic kidney disease (CKD) causes substantial global morbidity and increases
cardiovascular and all-cause mortality. Unlike other chronic diseases with established …

[HTML][HTML] The role of opioids in pain management in elderly patients with chronic kidney disease: a review article

S Dolati, F Tarighat, F Pashazadeh… - … and Pain Medicine, 2020 - ncbi.nlm.nih.gov
Chronic kidney disease (CKD) is a global public health problem. Pain is one of the most
generally experienced symptoms by CKD patients. Pain management is a key clinical …

[HTML][HTML] Analgesic use and associated adverse events in patients with chronic kidney disease: a systematic review and meta-analysis

E Lambourg, L Colvin, G Guthrie, H Walker… - British Journal of …, 2022 - Elsevier
Background Treating pain in the context of chronic kidney disease (CKD) is challenging
because of altered pharmacokinetics and pharmacodynamics, with an increased risk of …

[HTML][HTML] Association of Opioids and Nonsteroidal Anti-inflammatoryáDrugs With Outcomes in CKD: áFindings From the CRIC (Chronic Renal Insufficiency Cohort) …

M Zhan, RM Doerfler, D Xie, J Chen, HY Chen… - American Journal of …, 2020 - Elsevier
Rationale & Objective Safe analgesic choices are limited in chronic kidney disease (CKD).
We conducted a comparative analysis of harm from opioids versus nonsteroidal anti …

Associations of opioid prescriptions with death and hospitalization across the spectrum of estimated GFR

TK Novick, A Surapaneni, JI Shin… - Clinical Journal of the …, 2019 - journals.lww.com
Results The propensity-matched cohort included 46,246 patients prescribed either opioids
or NSAIDs between 2008 and 2017 (mean [SD] age, 54 [16] years; 56% female; 3% of black …

Drug stewardship in chronic kidney disease to achieve effective and safe medication use

RK Hall, R Kazancıoğlu, T Thanachayanont… - Nature Reviews …, 2024 - nature.com
People living with chronic kidney disease (CKD) often experience multimorbidity and require
polypharmacy. Kidney dysfunction can also alter the pharmacokinetics and …

[HTML][HTML] Frailty modifies the association between opioid use and mortality in chronic kidney disease patients with diabetes: a population-based cohort study

SY Lee, J Wang, CT Chao, KL Chien… - Aging (Albany NY …, 2020 - ncbi.nlm.nih.gov
The prevalence of chronic pain in patients with chronic kidney disease (CKD) and diabetes
mellitus is high and correlates with higher frailty risk, but satisfactory pain control frequently …

Non-steroidal anti-inflammatory drugs in chronic kidney disease and risk of acute adverse kidney events according to route of administration

SH Teo, NC Tan, JCJ Choo, JL Kwek… - … Urology and Nephrology, 2023 - Springer
Background Topical non-steroidal anti-inflammatory drugs (NSAIDs) have lower risks for
cardiovascular disease and gastrointestinal adverse effects compared to oral NSAIDs, but …

Two Weeks of Continuous Opioid Treatment in an Adenine-Induced Mouse Model of Chronic Kidney Disease Exacerbates the Bone Inflammatory State and Increases …

CE Metzger, GG Grecco, LY Tak, BK Atwood… - Calcified Tissue …, 2024 - Springer
Patients with chronic kidney disease (CKD) report high pain levels, but reduced renal
clearance eliminates many analgesic options; therefore, 30–50% of CKD patients have …

Nonsteroidal anti-inflammatory drugs in end-stage kidney disease: dangerous or underutilized?

KS Tang, AD Shah - Expert Opinion on Pharmacotherapy, 2021 - Taylor & Francis
Introduction: Nonsteroidal anti-inflammatory drugs (NSAIDs) are a popular class of
analgesic and anti-inflammatory medications, but their use is often avoided in end-stage …