Integrative omics approaches for biosynthetic pathway discovery in plants

KS Singh, JJJ van der Hooft, SCM van Wees… - Natural Product …, 2022 - pubs.rsc.org
Covering: up to 2022 With the emergence of large amounts of omics data, computational
approaches for the identification of plant natural product biosynthetic pathways and their …

Designing artificial synthetic promoters for accurate, smart, and versatile gene expression in plants

E Yasmeen, J Wang, M Riaz, L Zhang, K Zuo - Plant Communications, 2023 - cell.com
With the development of high-throughput biology techniques and artificial intelligence, it has
become increasingly feasible to design and construct artificial biological parts, modules …

Machine learning for plant stress modeling: A perspective towards hormesis management

AK Rico-Chávez, JA Franco, AA Fernandez-Jaramillo… - Plants, 2022 - mdpi.com
Plant stress is one of the most significant factors affecting plant fitness and, consequently,
food production. However, plant stress may also be profitable since it behaves hormetically; …

GRAND: a database of gene regulatory network models across human conditions

M Ben Guebila, CM Lopes-Ramos… - Nucleic Acids …, 2022 - academic.oup.com
Gene regulation plays a fundamental role in shaping tissue identity, function, and response
to perturbation. Regulatory processes are controlled by complex networks of interacting …

Using interactome big data to crack genetic mysteries and enhance future crop breeding

L Wu, L Han, Q Li, G Wang, H Zhang, L Li - Molecular plant, 2021 - cell.com
The functional genes underlying phenotypic variation and their interactions represent"
genetic mysteries". Understanding and utilizing these genetic mysteries are key solutions for …

Predicting and optimizing reactive oxygen species metabolism in Punica granatum L. through machine learning: role of exogenous GABA on antioxidant enzyme …

S Zarbakhsh, AR Shahsavar, A Afaghi… - BMC Plant …, 2024 - Springer
Background Drought and salinity stress have been proposed as the main environmental
factors threatening food security, as they adversely affect crops' agricultural productivity. As a …

Using single cell atlas data to reconstruct regulatory networks

Q Song, M Ruffalo, Z Bar-Joseph - Nucleic Acids Research, 2023 - academic.oup.com
Inference of global gene regulatory networks from omics data is a long-term goal of systems
biology. Most methods developed for inferring transcription factor (TF)–gene interactions …

Time-based systems biology approaches to capture and model dynamic gene regulatory networks

JM Alvarez, MD Brooks, J Swift… - Annual Review of Plant …, 2021 - annualreviews.org
All aspects of transcription and its regulation involve dynamic events. However, capturing
these dynamic events in gene regulatory networks (GRNs) offers both a promise and a …

Exploiting genomic features to improve the prediction of transcription factor-binding sites in plants

Q Rivière, M Corso, M Ciortan, G Noël… - Plant and Cell …, 2022 - academic.oup.com
The identification of transcription factor (TF) target genes is central in biology. A popular
approach is based on the location by pattern matching of potential cis-regulatory elements …

Biocuration of a Transcription Factors Network Involved in Submergence Tolerance during Seed Germination and Coleoptile Elongation in Rice (Oryza sativa)

S Naithani, B Mohanty, J Elser, P D'Eustachio… - Plants, 2023 - mdpi.com
Modeling biological processes and genetic-regulatory networks using in silico approaches
provides a valuable framework for understanding how genes and associated allelic and …