Introduction Indolizines are structural isomers with indoles. Although several indole-based
commercial drugs are available in the market, none of the indolizine-based drugs are …

A series of novel Ethyl-3-benzoyl-6, 8-difluoroindolizine-1-carboxylate analogues (4a-r)
were synthesized by reacting 3, 5-difluoropyridine, with phenacyl bromide to get quaternary …

Abstract A series of 1, 2, 3-trisubstituted indolizines (2a–2f, 3a–3d, and 4a–4c) were
screened for in vitro whole-cell anti-tubercular activity against the susceptible H37Rv and …

Candida albicans, an opportunistic fungal pathogen, frequently colonizes immune-
compromised patients and causes mild to severe systemic reactions. Only few antifungal …

A mild, greener approach via tandem-Michael-cyclization cascade reaction towards the
construction of a group of di-and tri-differently substituted indolizine with a broad scope of …

An efficient and facile method is developed to synthesize 3-benzoyl indolizines by two-
component reaction under microwave irradiation. A wide range of substrates could be …

Abstract Certain tetrahydropyrido [1, 2-a] quinolines and pyrroloquinoline homologs have
shown various biological activities such as antimicrobials, crop-protectings, diuretics …

A series of trisubstituted indolizine analogues has been designed as a result of a fragment-
based approach to target the inhibition of mycobacterial enoyl-acyl carrier protein reductase …

A one-pot three-component method for the synthesis of 3-substituted 2-trifluoromethyl-2, 3-
dihydroimidazo [1, 2-a] pyridin-3-yl analogues from 2-aminopyridine, substituted phenacyl …

According to WHO, in 2021, there was an estimation of 247 million malaria cases from 84
malaria-endemic countries. Globally an estimated count of 2 billion malaria cases and 11.7 …