Myofibroblast-induced remodeling of collagenous extracellular matrix is a key component of
our body's strategy to rapidly and efficiently repair damaged tissues; thus myofibroblast …

Proliferation of mammalian cells both in vivo and in vitro is dependent upon physiological
concentrations of extracellular Ca2+. Growth factor stimulation of quiescent cells at the G 0 G …

We measured changes in the molar concentration of cytosolic Ca2+ ([Ca2+] i) in individual
astrocytes in culture produced by the glutamate analog quisqualate (QA) and related …

THE temporal and spatial dynamics of intracellular signals and protein effectors are being
defined as a result of imaging using fluorescent reagents within living cells1–5. We have …

In order to determine the effect of calcium mobilization on mitogen-activated protein (MAP)
kinase activation, we have treated human foreskin fibroblasts (HSWP cells) and human …

This paper characterizes the early responses of epithelial cells to injury. Ca2+ is an
important early messenger that transiently increases in the cytoplasm of cells in response to …

Cytosolic calcium oscillations induced by a wide range of agonists, particularly those which
stimulate phosphoinositide metabolism, are the result of a periodic release of stored …

Mechanically scratching cell monolayers relieves contact inhibition and induces surviving
cells near the wound edge to move and proliferate. The present work was designed to test …

[Arg8]-vasopressin (AVP), at low concentrations (10–500 pM), stimulates oscillations in
intracellular Ca2+ concentration (Ca2+ spikes) in A7r5 rat aortic smooth muscle cells. Our …

We examined the involvement of tyrosine kinase activity in the bradykinin (BK)-mediated
signal transduction process. Immunoblots with anti-phosphotyrosine antibodies following BK …