Epilepsy is a group of chronic neurological disorders that have diverse etiologies but are
commonly characterized by spontaneous seizures and behavioral comorbidities. Although …

Prostanoids are cyclic, oxygenated products ofω3 andω6 20-and 22-carbon essential fatty
acids (FAs) that are formed enzymatically through “cyclooxygenases”. Prostaglandin …

Epilepsy is one of the most common chronic brain disorders worldwide, affecting 1% of
people across different ages and backgrounds. Epilepsy is defined as the sporadic …

Epilepsy is a group of enduring neurological disorder characterized by spontaneous and
recurrent seizures with heterogeneous etiology, clinical expression, severity, and prognosis …

A prominent area of neuroscience research over the past 20 years has been the acute
modulation of neuronal synaptic activity by Ca2+-dependent release of the transmitters ATP …

Lead (Pb) is a heavy metal with a proven neurotoxic effect. Exposure is particularly
dangerous to the developing brain in the pre-and neonatal periods. One postulated …

Elevated levels of cyclooxygenase‐2 (COX‐2) and prostaglandins (PGs) are involved in the
pathogenesis of Alzheimer's disease (AD), which is characterized by the accumulation of β …

Inflammation induced by innate immunity influences the development of T cell–mediated
autoimmunity in multiple sclerosis and its animal model, experimental autoimmune …

As the inducible terminal enzyme for prostaglandin E2 (PGE 2) synthesis, microsomal PGE
synthase-1 (mPGES-1) contributes to neuroinflammation and secondary brain injury after …

Seizure is a neurological disorder including hippocampal oxidative and inflammatory stress,
and glutamate toxicity. Thus, any agent (s) that mitigate (s) these events in hippocampus …