An insight of microRNAs performance in carcinogenesis and tumorigenesis; an overview of cancer therapy

K Babaei, S Shams, A Keymoradzadeh, S Vahidi… - Life sciences, 2020 - Elsevier
Importance of dysregulation and expression of microRNAs (miRNAs) has been confiemed in
many disorders comprising cancer. In this way, different approaches to induce …

Mechanisms of cancer stem cell therapy

AA Samadani, A Keymoradzdeh, S Shams… - Clinica Chimica …, 2020 - Elsevier
Cancer stem cells (CSCs) are responsible for carcinogenesis and tumorigenesis and are
involved in drug and radiation resistance, metastasis, tumor relapse and initiation …

Autoimmunity as an etiological factor of cancer: the transformative potential of chronic type 2 inflammation

CM Li, Z Chen - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Recent epidemiological studies have found an alarming trend of increased cancer incidence
in adults younger than 50 years of age and projected a substantial rise in cancer incidence …

Only serum pepsinogen I and pepsinogen I/II ratio are specific and sensitive biomarkers for screening of gastric cancer

F Mansour-Ghanaei, F Joukar, M Baghaee… - Biomolecular …, 2019 - degruyter.com
Purpose We aimed to determine optimal cut-off points of plasma levels of ghrelin and serum
levels of pepsinogen I, II, and their ratio for screening of gastric cancer (GC). Methods Blood …

[HTML][HTML] Therapeutic approach of Cancer stem cells (CSCs) in gastric adenocarcinoma; DNA methyltransferases enzymes in cancer targeted therapy

SE Norollahi, F Mansour-Ghanaei, F Joukar… - Biomedicine & …, 2019 - Elsevier
Cancer stem cells (CSCs) show a remarkable sub class of cancer cells population which
have a potential to organize and regulate stemness properties which possess a main …

Expression and clinical significance of SYNE1 and MAGI2 gene promoter methylation in gastric cancer

Y Qu, N Gao, T Wu - Medicine, 2021 - journals.lww.com
Gastric cancer is the fifth most common cancer and the third leading cause of cancer-related
mortality globally. Abnormal DNA methylation is closely related to gastric cancer. The …

[HTML][HTML] PD‑L1 gene promoter methylation represents a potential diagnostic marker in advanced gastric cancer

D Lv, C Xing, L Cao, Y Zhuo, T Wu… - Oncology …, 2020 - spandidos-publications.com
Gastric cancer is one of the most prevalent malignant tumors worldwide. Immunological
checkpoint inhibitors of the programmed death 1 (PD‑1)/programmed cell death‑ligand 1 …

Clinical value of pepsinogen in the screening, prevention, and diagnosis of gastric cancer

XL Han, CL Yi, JD Ma, Y He, LM Wu… - Laboratory …, 2022 - academic.oup.com
Objectives To compare the levels of serum pepsinogen (PG) in patients with gastric cancer
(GC), patients with atrophic gastritis (AG), and healthy donors. Also, we explored the clinical …

eEF2K as a novel metastatic and prognostic biomarker in gastric cancer patients

M Jiang, L Qi, K Jin, L Li, Y Wu, D Song, J Gan… - … -Research and Practice, 2021 - Elsevier
Background Although eukaryotic elongation factor 2 kinase (eEF2K) has been reported to
be a potential oncogenic factor in many human cancers, its usefulness as a clinical …

[HTML][HTML] Epigenetic profiling of MUTYH, KLF6, WNT1 and KLF4 genes in carcinogenesis and tumorigenesis of colorectal cancer

K Babaei, R Khaksar, T Zeinali, H Hemmati… - Biomedicine, 2019 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is distinguished by epigenetic elements like DNA methylation,
histone modification, histone acetylation and RNA remodeling which is related with genomic …