The impact of coronary physiology on contemporary clinical decision making

N Kogame, M Ono, H Kawashima, M Tomaniak… - Cardiovascular …, 2020 - jacc.org
Physiological assessment of coronary artery disease (CAD) has become one of the
cornerstones of decision making for myocardial revascularization, with a large body of …

[HTML][HTML] Validation of a novel non-hyperaemic index of coronary artery stenosis severity: the Resting Full-cycle Ratio (VALIDATE RFR) study

J Svanerud, JM Ahn, A Jeremias… - …, 2018 - eurointervention.pcronline.com
Aims: Randomised controlled trials have reported instantaneous wave-free ratio (iFR) to be
non-inferior to fractional flow reserve (FFR) for major adverse cardiovascular events at one …

Comparison of different diastolic resting indexes to iFR: are they all equal?

M Van't Veer, NHJ Pijls, B Hennigan, S Watkins… - Journal of the American …, 2017 - jacc.org
Background: Pressure measurement for the duration of the wave-free period (WFP) is
considered essential for resting-state physiological assessment of coronary stenosis severity …

Diagnostic performance of quantitative flow ratio in prospectively enrolled patients: an individual patient‐data meta‐analysis

J Westra, S Tu, G Campo, S Qiao… - Catheterization and …, 2019 - Wiley Online Library
Objectives We aimed to provide robust performance estimates for quantitative flow ratio
(QFR) in assessment of intermediary coronary lesions. Background Angiography‐based …

Non-hyperaemic pressure ratios to guide percutaneous coronary intervention

M Michail, U Thakur, O Mehta, JM Ramzy… - Open …, 2020 - openheart.bmj.com
The use of fractional flow reserve (FFR) in guiding revascularisation improves patient
outcomes and has been well-established in clinical guidelines. Despite this, the uptake of …

Fractional flow reserve/instantaneous wave-free ratio discordance in angiographically intermediate coronary stenoses: an analysis using Doppler-derived coronary …

CM Cook, A Jeremias, R Petraco, S Sen, S Nijjer… - JACC: Cardiovascular …, 2017 - jacc.org
Objectives: The study sought to determine the coronary flow characteristics of
angiographically intermediate stenoses classified as discordant by fractional flow reserve …

Safety of revascularization deferral of left main stenosis based on instantaneous wave-free ratio evaluation

T Warisawa, CM Cook, C Rajkumar, JP Howard… - Cardiovascular …, 2020 - jacc.org
Objectives The aim of this study was to assess the long-term clinical outcomes of patients
with left main coronary artery (LM) stenosis in whom treatment strategy was based on the …

Physiological pattern of disease assessed by pressure-wire pullback has an influence on fractional flow reserve/instantaneous wave-free ratio discordance: Insights …

T Warisawa, CM Cook, JP Howard… - Circulation …, 2019 - Am Heart Assoc
Background: Fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) disagree
on the hemodynamic significance of a coronary lesion in≈ 20% of cases. It is unknown …

Predictive factors of discordance between the instantaneous wave‐free ratio and fractional flow reserve

F Dérimay, NP Johnson… - Catheterization and …, 2019 - Wiley Online Library
Objectives To identify clinical, angiographic and hemodynamic predictors of discordance
between instantaneous wave‐free ratio (iFR) and fractional flow reserve (FFR). Background …

Similarity and difference of resting distal to aortic coronary pressure and instantaneous wave-free ratio

JM Lee, J Park, D Hwang, CH Kim, KH Choi… - Journal of the American …, 2017 - jacc.org
Background: Instantaneous wave-free ratio (iFR) has been used in clinical practice to
identify functionally significant stenosis and to guide treatment strategy. However, there are …