Opioids form an important component of general anesthesia and perioperative analgesia.
Discharge opioid prescriptions are identified as a contributor for persistent opioid use and …

Define chronic post-surgical pain (CPSP) according to the ICD-11 (International
Classification of Diseases, Eleventh Revision) classification and describe its impact on …

While US opioid prescribing has decreased 38% in the past decade, opioid deaths have
increased 300%. This opioid paradox is poorly recognized. Current approaches to opioid …

From April 2020 through April 2021, 75,673 Americans died from opioid overdoses, nearly
one-quarter of which directly involved prescription opioids. 1 This represents the first time …

Background: The purpose of this study was to determine the incidence, characteristics,
impact, and risk factors associated with persistent incisional pain. The hypothesis was that …

Background Long-term opioid use, which may have significant individual and societal
impacts, has been documented in up to 20% of patients after trauma or orthopaedic surgery …

Background Both preoperative psychological symptoms and chronic postsurgical pain
(CPSP) are prevalent conditions and major concerns among surgery patients, with …

Purpose To identify the proportion of patients with continued opioid use after total hip or
knee arthroplasty. Methods This systematic review and meta-analysis searched Embase …

Background: Opioid overprescribing after surgery is common. There is currently no universal
predictive tool available to accurately anticipate postdischarge opioid need in a patient …

Background Persistent opioid use (POU) can occur with opioid use after surgery or trauma.
Current systematic reviews include patients with previous exposure to opioids, meaning …