Potential of anti-cancer activity of secondary metabolic products from marine fungi

E Noman, MM Al-Shaibani, MA Bakhrebah… - Journal of Fungi, 2021 - mdpi.com
The promising feature of the fungi from the marine environment as a source for anticancer
agents belongs to the fungal ability to produce several compounds and enzymes which …

Anticancer Asparaginases: perspectives in using filamentous Fungi as cell factories

PHD Garcia, TA Costa-Silva, MM Gómez, FJ Contesini… - Catalysts, 2023 - mdpi.com
The enzyme L-asparaginase (L-asparagine amidohydrolase) catalyzes the breakdown of L-
asparagine into aspartate and ammonia, which leads to an anti-neoplastic activity stemming …

Penicillium and Talaromyces endophytes from Tillandsia catimbauensis, a bromeliad endemic in the Brazilian tropical dry forest, and their potential for l …

LF Silva, KTLS Freire, GR Araújo-Magalhães… - World Journal of …, 2018 - Springer
This study was conducted to report the richness of endophytic Penicillium and Talaromyces
species isolated from Tillandsia catimbauensis, a bromeliad endemic in the Brazilian …

Optimization of L-asparaginase production from some filamentous fungi with potential pharmaceutical properties

D Ali, S Ouf, M Eweis… - Egyptian Journal of …, 2018 - ejbo.journals.ekb.eg
ONE HUNDRED and forty three isolates related to 16 fungal species were recovered from
garden soil and indoor air of the medical chambers of Tumor Institute, Kasr El Ainy, Egypt …

Optimization of L-asparaginase production from Fusarium oxysporum F-S3 using irradiated pomegranate peel under solid-state fermentation

NS Abdel-Hamid, HH Abdel-Khalek… - Egyptian Journal of …, 2022 - journals.ekb.eg
L-asparaginase is an important enzyme used in the pharmaceutical and food industry and
can be produced by wide variety of microorganisms using affordable agro-based materials …

Biosynthesis and characterization of a novel penicillium janthinellum Biourge L-asparaginase as a diverse biological activities agent

HM Abo-Stait, SM Easa, FAA Zahra… - Egyptian …, 2021 - journals.lww.com
Materials and methods Eight recommended microbial isolates were screened for
biologically active L-ASP enzyme productivity. Optimization of the cultural conditions for …

Anticancer Efficacy of Purified Extracellular L-asparaginase from Aspergillus niger and Yield Enhancement by Agro-industrial Wastes

AS Yassein, AA El-Shahir - Egyptian Journal of Botany, 2022 - journals.ekb.eg
L-ASPARAGINASE enzyme is important medically as an anticancer agent and in the food
industry. The enzyme acts via degradation of l-asparagine and mitigation of acrylamide. This …

[PDF][PDF] Produção de L-asparaginase por Aspergillus niveus em Fermentação em Estado Sólido (FES)

IVS Amatto - 2019 - repositorio.unesp.br
A enzima L-asparaginase (L-asparagina amidohidrolase, EC 3.5. 1.1) promove a hidrólise
do aminoácido L-asparagina em ácido aspártico e amônia. Esta enzima é utilizada …

[PDF][PDF] Karakterisasi enzim L-asparaginase dari isolat fungi endofit genus rhizopus yang diisolasi dari daun tanaman tomat (Lycopersicum esculentum mill.)

E Hutaminingsih - 2020 - repository.wima.ac.id
L-asparaginase merupakan salah satu agen terapi dalam pengobatan kanker pada sistem
limfatik. L-asparaginase bekerja dengan cara menghidrolisis asam amino L-asparagin (Asn) …

Genetic diversity and post-translational modification analysis of L-asparaginase in six strains of Sordaria fimicola.

A Rasheed, R Arif, M Ishfaq, I Mobeen, MG Shahid… - 2020 - cabidigitallibrary.org
Filamentous fungi are a preferable source of production of L-asparaginase as compare to
other organisms. In the present study L-asparaginase gene NUC05624, which encode its …