How does hemodynamics affect rupture tissue mechanics in abdominal aortic aneurysm: Focus on wall shear stress derived parameters, time-averaged wall shear …

O Mutlu, HE Salman, H Al-Thani, A El-Menyar… - Computers in biology …, 2023 - Elsevier
An abdominal aortic aneurysm (AAA) is a critical health condition with a risk of rupture,
where the diameter of the aorta enlarges more than 50% of its normal diameter. The …

Insights on aortic aneurysm and dissection: Role of the extracellular environment in vascular homeostasis

Y Wang, P Gao, F Li, J Du - Journal of Molecular and Cellular Cardiology, 2022 - Elsevier
Aortic aneurysm and dissection (AAD) is a life-threatening medical condition associated with
high morbidity and mortality rates. Important mechanisms underlying AAD are the …

Prediction of wall stress and oxygen flow in patient-specific abdominal aortic aneurysms: the role of intraluminal thrombus

A Throop, M Bukac, R Zakerzadeh - Biomechanics and modeling in …, 2022 - Springer
In this study, the biomechanical role of intraluminal thrombus (ILT) in an abdominal aortic
aneurysm (AAA) is investigated. The implications of ILT in AAA are controversial in literature …

LINC00473 inhibits vascular smooth muscle cell viability to promote aneurysm formation via miR-212-5p/BASP1 axis

Z Tian, Y Sun, X Sun, J Wang, T Jiang - European journal of pharmacology, 2020 - Elsevier
Abdominal aortic aneurysm (AAA), as the most common type of aortic aneurysm, is closely
related to the proliferation and apoptosis ability of vascular smooth muscle cells (VSMCs) …

[HTML][HTML] Nucleolar stress induces a senescence-like phenotype in smooth muscle cells and promotes development of vascular degeneration

W Zhang, W Cheng, R Parlato, X Guo, X Cui… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Senescence of smooth muscle cells (SMCs) has a crucial role in the pathogenesis of
abdominal aortic aneurysm (AAA), a disease of vascular degeneration. Perturbation of …

Analysis of the wall shear stress in a generic aneurysm under pulsating and transitional flow conditions

A Bauer, M Bopp, S Jakirlic, C Tropea, AJ Krafft… - Experiments in …, 2020 - Springer
In this study, the flow through a generic abdominal aneurysm under realistic pulsating flow
conditions is examined with magnetic resonance velocimetry (MRV), laser Doppler …

Matricellular proteins: Potential biomarkers and mechanistic factors in aortic aneurysms

Z Li, X Cong, W Kong - Journal of Molecular and Cellular Cardiology, 2022 - Elsevier
Aortic aneurysms, including thoracic aortic aneurysms and abdominal aortic aneurysms, are
life-threatening macrovascular diseases with high mortality. The already known key …

The effects of geometric features of intraluminal thrombus on the vessel wall oxygen deprivation

B Carbino, A Guy, M Durka… - Frontiers in Bioengineering …, 2022 - frontiersin.org
The objective of this paper is to analyze the association of intraluminal thrombus (ILT)
presence and morphology with oxygen transport in abdominal aortic aneurysms (AAA) and …

Analyzing the effects of multi-layered porous intraluminal thrombus on oxygen flow in abdominal aortic aneurysms

A Throop, D Badr, M Durka, M Bukač, R Zakerzadeh - Oxygen, 2022 - mdpi.com
Determination of abdominal aortic aneurysm (AAA) rupture risk involves the accurate
prediction of mechanical stresses acting on the arterial tissue, as well as the wall strength …

Abdominal aortic aneurysm and virus infection: A potential causative role for cytomegalovirus infection?

A Jabłońska, B Zagrapan, E Paradowska… - Journal of medical …, 2021 - Wiley Online Library
An abdominal aortic aneurysm (AAA) is a multifactorial disease with a variety of genetic and
environmental risk factors, but the exact mechanism of AAA formation and progression is still …