Bacterial ribonucleases and their roles in RNA metabolism

DH Bechhofer, MP Deutscher - Critical reviews in biochemistry and …, 2019 - Taylor & Francis
Ribonucleases (RNases) are mediators in most reactions of RNA metabolism. In recent
years, there has been a surge of new information about RNases and the roles they play in …

Major 3′–5′ exoribonucleases in the metabolism of coding and non-coding RNA

RF Dos Santos, AP Quendera, S Boavida… - Progress in molecular …, 2018 - Elsevier
5′ exoribonucleases are key enzymes in the degradation of superfluous or aberrant RNAs
and in the maturation of precursor RNAs into their functional forms. The major bacterial 3 …

Structural basis of ribosomal 30S subunit degradation by RNase R

L Dimitrova-Paternoga, S Kasvandik, B Beckert… - Nature, 2024 - nature.com
Protein synthesis is a major energy-consuming process of the cell that requires the
controlled production,–and turnover, of ribosomes. Although the past few years have seen …

circRNA circAF4 functions as an oncogene to regulate MLL-AF4 fusion protein expression and inhibit MLL leukemia progression

W Huang, K Fang, TQ Chen, ZC Zeng, YM Sun… - Journal of hematology & …, 2019 - Springer
Abstract Background Circular RNAs (circRNAs) represent a type of endogenous noncoding
RNAs that are generated by back-splicing events and favor repetitive sequences. Recent …

A type II toxin–antitoxin system is responsible for the cell death at low temperature in Pseudomonas syringae Lz4W lacking RNase R

P Mittal, AK Sinha, A Pandiyan, L Kumari… - Journal of Biological …, 2024 - jbc.org
RNase R (encoded by the rnr gene) is a highly processive 3′→ 5′ exoribonuclease
essential for the growth of the psychrotrophic bacterium Pseudomonas syringae Lz4W at low …

The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction

A Luqman-Fatah, Y Watanabe, K Uno… - Nature …, 2023 - nature.com
Some interferon stimulated genes (ISGs) encode proteins that inhibit LINE-1 (L1)
retrotransposition. Here, we use immunoprecipitation followed by liquid chromatography …

Role of hsa_circ_0000280 in regulating vascular smooth muscle cell function and attenuating neointimal hyperplasia via ELAVL1

Z Wang, H Wang, C Guo, F Yu, Y Zhang, L Qiao… - Cellular and Molecular …, 2023 - Springer
The pathological proliferation of cells in vascular smooth muscle underlies neointimal
hyperplasia (NIH) development during atherosclerosis. Circular RNAs (circRNAs), which …

Hibernation-promoting factor sequesters Staphylococcus aureus ribosomes to antagonize RNase R-mediated nucleolytic degradation

A Lipońska, MNF Yap - MBio, 2021 - Am Soc Microbiol
Bacterial and eukaryotic hibernation factors prevent translation by physically blocking the
decoding center of ribosomes, a phenomenon called ribosome hibernation that often occurs …

Organellar and secretory ribonucleases: major players in plant RNA homeostasis

GC MacIntosh, B Castandet - Plant Physiology, 2020 - academic.oup.com
Organellar and Secretory Ribonucleases: Major Players in Plant RNA Homeostasis | Plant
Physiology | Oxford Academic Skip to Main Content Advertisement Oxford Academic Journals …

Omnipresent Maxwell's demons orchestrate information management in living cells

G Boël, O Danot, V De Lorenzo… - Microbial …, 2019 - Wiley Online Library
The development of synthetic biology calls for accurate understanding of the critical
functions that allow construction and operation of a living cell. Besides coding for ubiquitous …