In the CNS, iron in several proteins is involved in many important processes such as oxygen
transportation, oxidative phosphorylation, myelin production, and the synthesis and …

Neuroplasticity can be defined as the ability of the nervous system to respond to intrinsic or
extrinsic stimuli by reorganizing its structure, function and connections. Major advances in …

Abstract The Adolescent Brain Cognitive Development (ABCD) Study is an ongoing,
nationwide study of the effects of environmental influences on behavioral and brain …

Background Identifying individuals at risk for developing Alzheimer disease (AD) is of utmost
importance. Although genetic studies have identified AD-associated SNPs in APOE and …

Alzheimer's disease (AD) is classically defined as a dual clinicopathological entity. The
recent advances in use of reliable biomarkers of AD that provide in-vivo evidence of the …

There is considerable debate whether Alzheimer's disease (AD) originates in basal
forebrain or entorhinal cortex. Here we examined whether longitudinal decreases in basal …

The structure of the brain is constantly changing from birth throughout the lifetime, meaning
that normal aging, free from dementia, is associated with structural brain changes. This …

Longitudinal neuroimaging (LNI) studies are rapidly becoming more prevalent and growing
in size. Today, no standardized computational tools exist for the analysis of LNI data and …

Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing,
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …

Early-life development is characterized by dramatic changes, impacting lifespan function
more than changes in any other period. Developmental origins of neurocognitive late-life …