Disentangling interactions in the microbiome: a network perspective

M Layeghifard, DM Hwang, DS Guttman - Trends in microbiology, 2017 - cell.com
Microbiota are now widely recognized as being central players in the health of all organisms
and ecosystems, and subsequently have been the subject of intense study. However …

Malnutrition and gut microbiota in children

I Iddrisu, A Monteagudo-Mera, C Poveda, S Pyle… - Nutrients, 2021 - mdpi.com
Malnutrition continues to threaten the lives of millions across the world, with children being
hardest hit. Although inadequate access to food and infectious disease are the primary …

Microbiome differential abundance methods produce different results across 38 datasets

JT Nearing, GM Douglas, MG Hayes… - Nature …, 2022 - nature.com
Identifying differentially abundant microbes is a common goal of microbiome studies.
Multiple methods are used interchangeably for this purpose in the literature. Yet, there are …

A self-powered ingestible wireless biosensing system for real-time in situ monitoring of gastrointestinal tract metabolites

E De la Paz, NH Maganti, A Trifonov, I Jeerapan… - Nature …, 2022 - nature.com
Abstract Information related to the diverse and dynamic metabolite composition of the small
intestine is crucial for the diagnosis and treatment of various diseases. However, our current …

Normalization and microbial differential abundance strategies depend upon data characteristics

S Weiss, ZZ Xu, S Peddada, A Amir, K Bittinger… - Microbiome, 2017 - Springer
Background Data from 16S ribosomal RNA (rRNA) amplicon sequencing present
challenges to ecological and statistical interpretation. In particular, library sizes often vary …

[HTML][HTML] Gut microbiota in various childhood disorders: Implication and indications

NK Saeed, M Al-Beltagi, AS Bediwy… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Gut microbiota has a significant role in gut development, maturation, and immune system
differentiation. It exerts considerable effects on the child's physical and mental development …

Oral phage therapy of acute bacterial diarrhea with two coliphage preparations: a randomized trial in children from Bangladesh

SA Sarker, S Sultana, G Reuteler, D Moine… - …, 2016 - thelancet.com
Background Antibiotic resistance is rising in important bacterial pathogens. Phage therapy
(PT), the use of bacterial viruses infecting the pathogen in a species-specific way, is a …

Impact of childhood malnutrition on host defense and infection

MK Ibrahim, M Zambruni, CL Melby… - Clinical microbiology …, 2017 - Am Soc Microbiol
The global impact of childhood malnutrition is staggering. The synergism between
malnutrition and infection contributes substantially to childhood morbidity and mortality …

The clinical evidence for postbiotics as microbial therapeutics

A Mosca, AT Abreu Y Abreu, KA Gwee, G Ianiro… - Gut …, 2022 - Taylor & Francis
An optimally operating microbiome supports protective, metabolic, and immune functions,
but disruptions produce metabolites and toxins which can be involved in many conditions …

The global problem of childhood diarrhoeal diseases: emerging strategies in prevention and management

M Mokomane, I Kasvosve, E Melo… - Therapeutic …, 2018 - journals.sagepub.com
Acute diarrhoeal diseases remain a leading cause of global morbidity and mortality
particularly among young children in resource-limited countries. Recent large studies …