Type 2 diabetes mellitus and sepsis: state of the art, certainties and missing evidence

E Costantini, M Carlin, M Porta, MF Brizzi - Acta Diabetologica, 2021 - Springer
Diabetes and sepsis are important causes of morbidity and mortality worldwide, and diabetic
patients represent the largest population experiencing post-sepsis complications and rising …

Impact of diabetes mellitus on outcomes of patients with sepsis: an updated systematic review and meta-analysis

L Jiang, M Cheng - Diabetology & Metabolic Syndrome, 2022 - Springer
Background The effect of concurrent diabetes on the outcome of sepsis is not conclusively
known. A meta-analysis published in 2017 indicated that diabetes did not influence the …

Hypoglycemia and mortality in sepsis patients: A systematic review and meta-analysis

J Wang, CK Zhu, JQ Yu, R Tan, PL Yang - Heart & Lung, 2021 - Elsevier
Background Hypoglycemia frequently occurs in patients with sepsis. The status of prognosis
of sepsis patients varies with the cause of hypoglycemia. Objective A meta-analysis was …

Endothelial glycocalyx disorders may be associated with extended inflammation during endotoxemia in a diabetic mouse model

S Sampei, H Okada, H Tomita, C Takada… - Frontiers in cell and …, 2021 - frontiersin.org
In diabetes mellitus (DM) patients, the morbidity of infectious disease is increased, and these
infections can easily progress from local to systemic infection. Sepsis is a characteristic of …

Acute-to-chronic glycemic ratio as a predictor of COVID-19 severity and mortality

J Ramon, G Llauradó, R Güerri, E Climent… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE To evaluate the association between acute-to-chronic (A/C) glycemic ratio and
mortality and severity outcomes for patients with type 2 diabetes (T2D) hospitalized with …

Sepsis‐associated hypoglycemia on admission is associated with increased mortality in intensive care unit patients

Y Mitsuyama, K Shimizu, S Komukai… - Acute Medicine & …, 2022 - Wiley Online Library
Aim Hyperglycemia is a common response to acute illness, but it is not often seen in critical
conditions. The frequency and cause of hypoglycemia in septic patients have not been well …

Intensive insulin therapy in sepsis patients: better data enables better intervention

L Wang, M Wang, J Du, Z Gong - Heliyon, 2023 - cell.com
In clinics, sepsis is a critical disease that often develops into shock and multiple organ
dysfunction, leading to a serious threat of death. Patients with sepsis are often accompanied …

Clotting dysfunction in sepsis: a role for ROS and potential for therapeutic intervention

ME Lopes-Pires, JO Frade-Guanaes, GJ Quinlan - Antioxidants, 2021 - mdpi.com
Sepsis is regarded as one of the main causes of death among the critically ill. Pathogen
infection results in a host-mediated pro-inflammatory response to fight infection; as part of …

Machine learning for early outcome prediction in septic patients in the emergency department

M Greco, PF Caruso, S Spano, G Citterio, A Desai… - Algorithms, 2023 - mdpi.com
Background: Sepsis is one of the major causes of in-hospital death, and is frequent in
patients presenting to the emergency department (ED). Early identification of high-risk septic …

Diabetes is associated with poor short-term prognosis in patients with hepatitis B virus-related acute-on-chronic liver failure

H Hu, X Hu, C Tian, Y Zhu, Y Liu, Q Cheng… - Hepatology …, 2021 - Springer
Background/purpose Associations between the disturbances in glucose homeostasis and
prognosis in patients with hepatitis B virus (HBV)-related acute-on-chronic liver failure …