The initial development of cytomegalovirus (CMV) as a vaccine vector for HIV/simian
immunodeficiency virus (SIV) was predicated on its potential to pre-position high-frequency …

Conditionally replicating viruses (CRVs) are a type of virus with one or more essential gene
functions that are impaired resulting in the disruption of viral genome replication, protein …

Identifying a vaccine capable of generating durable T cell responses that target mutationally
vulnerable epitopes and that can rapidly intercept infecting or rebounding virus remains a …

Mucosal surfaces that line the respiratory, gastrointestinal and genitourinary tracts are the
major interfaces between the immune system and the environment. Their unique …

Liver fibrosis is an important pathological process in chronic liver disease and cirrhosis.
Recent studies have found a close association between intestinal microbiota and the …