Diabetic nephropathy (DN) often leads to end-stage renal disease. Oxidative stress
demonstrates a crucial act in the onset and progression of DN, which triggers various …

Diabetic nephropathy (DN) is the most common chronic kidney disease. Accumulation of
glucose and metabolites activates resident macrophages in kidneys. Resident macrophages …

Diabetic kidney disease (DKD) is the most common cause of end-stage kidney disease
(ESKD) in the United States. Risk factor modification, such as tight control of blood glucose …

Although diabetic kidney disease (DKD) remains the leading cause of end-stage kidney
disease eventually requiring chronic kidney replacement therapy, the prevalence of DKD …

Background: Diabetic kidney disease (DKD) is the most common cause of the end-stage
renal disease (ESRD). Regardless of intensive treatments with hyperglycemic control, blood …

Hyaluronan (HA) is a ubiquitous glycosaminoglycan of the extracellular matrix. It is present
in the endothelial glycocalyx covering the apical surface of endothelial cells. The endothelial …

Reports suggest a role of endothelial dysfunction and loss of endothelial barrier function in
COVID-19. It is well established that the endothelial glycocalyx-degrading enzyme …

The endothelial glycocalyx (EG), which covers the apical surface of the endothelial cells and
floats into the lumen of the vessels, is a key player in vascular integrity and cardiovascular …

Diabetic kidney disease (DKD) is the primary cause of chronic kidney disease around the
globe and is one of the main complications in patients with type 1 and 2 diabetes. The …

Diabetes is considered a major burden on the healthcare system of Western and non‐
Western societies with the disease reaching epidemic proportions globally. Diabetic patients …