The centenary of insulin discovery represents an important opportunity to transform diabetes
from a fatal diagnosis into a medically manageable chronic condition. Insulin is a key …

Liver steatosis without alcohol consumption, namely, nonalcoholic fatty liver disease
(NAFLD), is a common hepatic condition that encompasses a wide spectrum of …

Oxidative stress and chronic inflammation are known to be associated with the development
of metabolic diseases, including diabetes. Oxidative stress, an imbalance between oxidative …

Obesity and insulin resistance are the major predisposing factors to comorbidities, such as
Type 2 diabetes, nonalcoholic fatty liver disease, cardiovascular and neurodegenerative …

One in 10 persons in the world aged 40 years and older will develop the syndrome of
HFpEF (heart failure with preserved ejection fraction), the most common form of chronic …

Diabetes mellitus is a significant clinical and therapeutic problem because it can lead to
serious long-term complications. Its pathogenesis is not fully understood, but there are …

Despite its very low level in humans, selenium plays an important and unique role among
the (semi) metal trace essential elements because it is the only one for which incorporation …

Antioxidant supplements are commonly consumed by endurance athletes to minimize
exercise-induced oxidative stress, with the intention of enhancing recovery and improving …

The obesity epidemic has led researchers and clinicians to reconsider the etiology of this
disease and precisely decipher its molecular mechanisms. The excessive accumulation of …

Obesity-induced chronic inflammation is a key component in the pathogenesis of insulin
resistance and the Metabolic syndrome. In this review, we focus on the interconnection …