Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF)
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …

Despite the recognition of Pseudomonas aeruginosa as an opportunistic pathogen, no
vaccine against this bacteria has come to market. This review describes the current state-of …

Autoantibodies are a hallmark of both autoimmune disease and cancer, but they also occur
in healthy individuals. Here, we perform a meta-analysis of nine datasets and focus on the …

Systems biology is an emerging discipline that combines high-content, multiplexed
measurements with informatic and computational modeling methods to better understand …

Protein microarrays are crucial tools in the study of proteins in an unbiased, high-throughput
manner, as they allow for characterization of up to thousands of individually purified proteins …

An important question regarding the biologic implications of antibiotic-resistant microbes is
how resistance impacts the organism's overall fitness and virulence. Currently it is generally …

Rationale: New vaccine approaches are needed for Pseudomonas aeruginosa, which
continues to be a major cause of serious pulmonary infections. Although Th17 cells can …

Background Drug treatments and vaccine designs against the opportunistic human
pathogen Pseudomonas aeruginosa have multiple issues, all associated with the diverse …

Pseudomonas aeruginosa is among top critical nosocomial infectious agents due to its
persistent infections and tendency for acquiring drug resistance mechanisms. To date, there …

Diabetes mellitus (DM) is a group of metabolic diseases marked by hyperglycemia, which
increases the risk of systemic infections. DM patients are at greater risk of hospitalization …