The cytoskeleton—a complex interacting meshwork

T Hohmann, F Dehghani - Cells, 2019 - mdpi.com
The cytoskeleton of animal cells is one of the most complicated and functionally versatile
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …

Actin dynamics, architecture, and mechanics in cell motility

L Blanchoin, R Boujemaa-Paterski… - Physiological …, 2014 - journals.physiology.org
Tight coupling between biochemical and mechanical properties of the actin cytoskeleton
drives a large range of cellular processes including polarity establishment, morphogenesis …

Stretchable hydrogels with low hysteresis and anti-fatigue fracture based on polyprotein cross-linkers

H Lei, L Dong, Y Li, J Zhang, H Chen, J Wu… - Nature …, 2020 - nature.com
Hydrogel-based devices are widely used as flexible electronics, biosensors, soft robots, and
intelligent human-machine interfaces. In these applications, high stretchability, low …

The microtubule cytoskeleton in cardiac mechanics and heart failure

MA Caporizzo, BL Prosser - Nature Reviews Cardiology, 2022 - nature.com
The microtubule network of cardiac muscle cells has unique architectural and biophysical
features to accommodate the demands of the working heart. Advances in live-cell imaging …

Modeling semiflexible polymer networks

CP Broedersz, FC MacKintosh - Reviews of Modern Physics, 2014 - APS
This is an overview of theoretical approaches to semiflexible polymers and their networks.
Such semiflexible polymers have large bending rigidities that can compete with the entropic …

Cell mechanics and the cytoskeleton

DA Fletcher, RD Mullins - Nature, 2010 - nature.com
The ability of a eukaryotic cell to resist deformation, to transport intracellular cargo and to
change shape during movement depends on the cytoskeleton, an interconnected network of …

Force feedback controls motor activity and mechanical properties of self-assembling branched actin networks

P Bieling, J Weichsel, R McGorty, P Jreij, B Huang… - Cell, 2016 - cell.com
Branched actin networks—created by the Arp2/3 complex, capping protein, and a nucleation
promoting factor—generate and transmit forces required for many cellular processes, but …

From mechanical resilience to active material properties in biopolymer networks

F Burla, Y Mulla, BE Vos, A Aufderhorst-Roberts… - Nature Reviews …, 2019 - nature.com
The cells and tissues that make up our body manage contradictory mechanical demands. It
is crucial for their survival to be able to withstand large mechanical loads, but it is equally …

Molecular mechanisms of cellular mechanosensing

T Luo, K Mohan, PA Iglesias, DN Robinson - Nature materials, 2013 - nature.com
Mechanical forces direct a host of cellular and tissue processes. Although much emphasis
has been placed on cell-adhesion complexes as force sensors, the forces must nevertheless …

An active biopolymer network controlled by molecular motors

GH Koenderink, Z Dogic, F Nakamura… - Proceedings of the …, 2009 - National Acad Sciences
We describe an active polymer network in which processive molecular motors control
network elasticity. This system consists of actin filaments cross-linked by filamin A (FLNa) …