It has been known for a long time that thyroid hormones have prominent effects on hepatic
fatty acid and cholesterol synthesis and metabolism. Indeed, hypothyroidism has been …

Background: Thyroid hormones (THs) exert a strong influence on mammalian lipid
metabolism at the systemic and hepatic levels by virtue of their roles in regulating circulating …

Metabolic syndrome (MetS) and thyroid dysfunction are common in clinical practice. The
objectives of this review are to discuss some proposed mechanisms by which thyroid …

Summary apoE-deficient mice have been created by homologous recombination in ES cells.
On a low fat, low cholesterol chow diet these animals have plasma cholesterol levels of 494 …

Hypothyroidism is closely associated with increased serum total cholesterol (TC), low-
density lipoprotein cholesterol (LDL-C) and triglyceride (TG). The thyroid gland plays an …

There is a wide variety of kinds of lipids, and complex structures which determine the
diversity and complexity of their functions. With the basic characteristic of water insolubility …

The fidelity of biological information flow is critical. Deoxyribonucleic acid (DNA) replication,
with its attendant proofreading and repair processes, has an error level in the range of 10-8 …

Hypothyroidism is often associated with elevated serum levels of total cholesterol, low-
density lipoprotein cholesterol (LDL-C) and triglycerides. Thyroid hormone (TH) affects the …

For the past 5 years, investigators from many different laboratories have contributed to a
greatly increased understanding of two very important lipid-carrying proteins in plasma--apo …

Two different isoproteins are encoded by the apolipoprotein (apo) B gene, apoB-48 and
apoB-100. ApoB-48, core component of intestinally derived chylomicrons, has an …