The burgeoning demand for novel cytotoxic drugs possessing improved bioavailability and
safety profiles has spurred the hybridization of various pharmacophores in the past decades …

Dimethylamine (DMA) derivatives represent a promising class of compounds with significant
potential in the field of medicinal chemistry. DMA derivatives exhibit a diverse range of …

It has been established that the Hydrazone derivatives have important pharmacological
effects. In the first step, hydrazine (NH 2 NH 2) reacts with a compound containing a …

Schiff bases tethered with sulfonamide functionality (6a-l) are reported as potential
anticancer agents and apoptotic inducers. The anti-proliferative activities of the tested Schiff …

A series of hydrazide‐hydrazone imine derivative compounds (3a–k) were synthesized and
their structures characterized using FTIR, 1H, and 13C (NMR) spectroscopic methods. In …

The reaction of equimolar equivalents of 1-(4-methoxyphenyl)-5-methyl-1 H-1, 2, 3-triazole-4-
carbohydrazide (1) and 2-acetylbenzofuran (2) in anhydrous ethanol containing a catalytic …

Background Evasion of pyroptosis is an effective survival strategy employed by cancer cells
to evade immune cell attacks and drug-induced cytotoxicity. Exploring potent molecules …

Hydrazones, which are azomethine-containing active chemicals with a single bondN (H)
Ndouble bondCH group, are extensively researched due to their versatility in pharmacology …

Various cancer-associated morbidities remain a growing global health challenge, resulting
in a significant burden on healthcare systems worldwide due to high mortality rates and a …

New resveratrol-based Schiff base derivatives (1, 2, 4-triazole Schiff base derivatives 5a-d
and hydrazide Schiff base derivatives 7a-d) were designed, synthesized via Schiff base …