Ionotropic GABA transmission is mediated by anion (mainly Cl−)-permeable GABAA receptors (GABAARs). In immature neurons, GABA exerts depolarizing and sometimes …
W Löscher, GJ Sills, HS White - Epilepsia, 2021 - Wiley Online Library
Since 1955, several alkyl‐carbamates have been developed for the treatment of anxiety and epilepsy, including meprobamate, flupirtine, felbamate, retigabine, carisbamate, and …
Y Guo, J Du, C Xiao, P Xiang, Y Deng… - European Journal of …, 2021 - Wiley Online Library
Background Relationships between iron‐dependent ferroptosis and nerve system diseases have been recently revealed. However, the role of ferroptosis in neuropathic pain (NeP) …
W Zhang, Z Zhu, Z Liu - Brain Research Bulletin, 2020 - Elsevier
Neuropathic Pain (NPP) is caused by direct or indirect damage to the nervous system and is a common symptom of many diseases. Clinically, drugs are usually used to suppress pain …
J Bielewicz, M Kamieniak, M Szymoniuk, J Litak… - Journal of Clinical …, 2023 - mdpi.com
Neuropathic pain is generally defined as a non-physiological pain experience caused by damage to the nervous system. It can occur spontaneously, as a reaction to a given stimulus …
Despite the rapid advance over the past decades to design effective therapeutic pharmacological interventions, chronic pain remains to be an unresolved healthcare …
M Balogh, C Aguilar, NT Nguyen, AJ Shepherd - Pain reports, 2021 - journals.lww.com
Growing evidence implicates the renin–angiotensin system (RAS) in multiple facets of neuropathic pain (NP). This narrative review focuses primarily on the major bioactive RAS …
X Li, Q Wang, J Ding, S Wang, C Dong… - Molecular …, 2020 - journals.sagepub.com
Neuropathic pain is one of the most frequently stated complications after spinal cord injury. In post-spinal cord injury, the decrease of gamma aminobutyric acid synthesis within the …
Neuropathic pain (NPP) is a common symptom of most diseases in clinic, which seriously affects the mental health of patients and brings certain pain to patients. Due to its …