Results from recent clinical trials of antibodies that target amyloid-β (Aβ) for Alzheimer's
disease have created excitement and have been heralded as corroboration of the amyloid …

Neurogenesis in adult primate neocortex: an evaluation of the evidence | Nature Reviews
Neuroscience Skip to main content Thank you for visiting nature.com. You are using a browser …

Alzheimer's disease, the cause of one of the most common types of dementia, is a brain
disorder affecting the elderly and is characterized by the formation of two main protein …

There are many lines of evidence showing that oxidative stress and aberrant mitogenic
changes have important roles in the pathogenesis of Alzheimer's disease (AD). However …

Certain cytokines, the prototype being the highly pleiotropic TNF, have many homeostatic
physiological roles, are involved in innate immunity, and cause inflammation when in …

The study of neurogenesis in the adult brain is among the most exciting and fastest moving
areas of neuroscience today. In contrast to the high rate of neurogenesis in some …

We reported previously that the carbohydrate domain of the amyloid precursor protein is
involved in amyloid precursor protein (APP)-APP interactions. Functional in vitro studies …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the central
nervous system (CNS) which is the most common cause of dementia in the elderly. It is …

Humanin (HN) inhibits neuronal death induced by various Alzheimer's disease (AD)-related
insults via an unknown receptor on cell membranes. Our earlier study indicated that the …

Background Supported by compelling genetic data regarding early-onset familial Alzheimer
disease (AD), the amyloid β-peptide (Aβ)–centric theory holds that Aβ is involved in the …