Background Globally, children under 15 years represent approximately 12% of new
tuberculosis cases, but 16% of the estimated 1.4 million deaths. This higher share of …

Background: Current immunodiagnostic tests for tuberculosis (TB) are based on the
detection of an immune response toward mycobacterial antigens injected into the skin or …

The diagnosis of tuberculosis (TB) in children is difficult because of the low sensitivity and
specificity of traditional microbiology techniques in this age group. Whereas in adults the …

A quarter of the global human population is estimated to be latently infected by
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB). TB remains the …

The tuberculin skin test and interferon-gamma release assays have limitations in diagnosing
tuberculosis (TB), particularly in children. This study investigated the performance of …

Background Paediatric pleural tuberculosis (TB) is a paucibacillary disease, which
increases the difficulty of examination. We aimed to assess the performance of pleural fluid …

Background Tuberculosis (TB) is a public health problem worldwide. Characterizing its
trends over time is a useful tool for decision-makers to assess the efficiency of TB control …

Chest radiographs (CXR) have played an important and evolving role in diagnosis,
classification and management of pediatric pulmonary tuberculosis (TB). During the pre …

Background Human immunodeficiency virus (HIV)–infected individuals have a higher risk of
developing active tuberculosis (TB) than HIV-uninfected individuals, but the mechanisms …

Background Tuberculosis (TB) is one of the most common causes of mortality globally with a
steady rise in paediatric cases in the past decade. Laboratory methods of diagnosing TB …