The absorption of oral drugs is frequently plagued by significant variability with potentially
serious therapeutic consequences. The source of variability can be traced back to …

Pediatric Intestinal Failure | New England Journal of Medicine Skip to main content The New
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …

Abstract The European Society for Clinical Nutrition and Metabolism defined intestinal
failure (IF) as “the reduction of gut function below the minimum necessary for the absorption …

Parenteral nutrition (PN) represents one of the most notable achievements of modern
medicine, serving as a therapeutic modality for all age groups across the healthcare …

OBJECTIVES: In the pivotal 24-week, phase III, placebo-controlled trial, teduglutide
significantly reduced parenteral support (PS) requirements in patients with short bowel …

Background & aims Intestinal failure (IF) is defined as “the reduction of gut function below
the minimum necessary for the absorption of macronutrients and/or water and electrolytes …

Intestinal surface changes in size and function, but what propels these alterations and what
are their metabolic consequences is unknown. Here we report that the food amount is a …

Surgery involving the gastrointestinal tract continues to prove challenging because of the
persistence of unpredictable complications such as anastomotic leakage and life …

The small intestine displays marked anatomical and functional plasticity that includes
adaptive alterations in adult gut morphology, enteroendocrine cell profile and their hormone …

The human small intestine is organized with a proximal‐to‐distal gradient of mucosal
structure and nutrient processing capacity. However, certain nutrients undergo site‐specific …