SARS-CoV-2 is the virus responsible for the global COVID19 pandemic. We review what is
known about the origin of this virus, detected in China at the end of December 2019. The …

The continuous development of sequencing technologies has enabled researchers to obtain
large amounts of biological sequence data, and this has resulted in increasing demands for …

Motivation Multiple sequence alignment (MSA) is a fundamental problem in bioinformatics.
The quality of alignment will affect downstream analysis. MAFFT has adopted the Fast …

Background: In previous studies we have shown that severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) replicates in vitro in bacterial growth medium, that the viral …

Hotel quarantine for international travelers has been used to prevent coronavirus disease
spread into Australia. A quarantine hotel–associated community outbreak was detected in …

Abstract The Balanced Minimum Evolution Problem (BMEP) is an APX-hard network design
problem that consists of finding a minimum length unrooted binary tree (also called a …

Phylogenetics is now fundamental in life sciences, providing insights into the earliest
branches of life and the origins and spread of epidemics. However, finding suitable …

Next-generation sequencing has been essential to the global response to the COVID-19
pandemic. As of January 2022, nearly 7 million severe acute respiratory syndrome …

SARS-CoV-2 genomic sequencing efforts have scaled dramatically to address the current
global pandemic and aid public health. However, autonomous genome annotation of SARS …

Although the global response to COVID-19 has not been entirely unified, the opportunity
arises to assess the impact of regional public health interventions and to classify strategies …