[HTML][HTML] The roles of white adipose tissue and liver NADPH in dietary restriction-induced longevity
LE Jamerson, PC Bradshaw - Antioxidants, 2024 - mdpi.com
Dietary restriction (DR) protocols frequently employ intermittent fasting. Following a period of
fasting, meal consumption increases lipogenic gene expression, including that of NADPH …
fasting, meal consumption increases lipogenic gene expression, including that of NADPH …
The potential role and therapeutic relevance of cellular senescence in skeletal pathophysiology
B Li, P Lyu, J Tang, J Li, T Ouchi, Y Fan… - The Journals of …, 2024 - academic.oup.com
Biological aging profoundly impairs the homeostasis of the skeletal system. Cellular
senescence, a hallmark of biological aging, plays an instrumental role in bone disease. The …
senescence, a hallmark of biological aging, plays an instrumental role in bone disease. The …
Oxidative stress and regulation of adipogenic differentiation capacity by sirtuins in adipose stem cells derived from female patients of advancing age
A Bernhardt, A Jamil, MT Morshed, P Ponnath… - Scientific Reports, 2024 - nature.com
Patient age is critical for mesenchymal stem cell quality and differentiation capacity. We
demonstrate that proliferation and adipogenic capacity of subcutaneous adipose stem cells …
demonstrate that proliferation and adipogenic capacity of subcutaneous adipose stem cells …
Lactate-induced lactylation and cardiometabolic diseases: From epigenetic regulation to therapeutics
J Lin, J Ren - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2024 - Elsevier
Cardiometabolic diseases (CMDs) denote a cadre of chronic and devastating
cardiovascular anomalies routed from metabolic derangements including obesity, type 2 …
cardiovascular anomalies routed from metabolic derangements including obesity, type 2 …
Increased hydrogen sulfide turnover serves a cytoprotective role during the development of replicative senescence
A Kieronska-Rudek, K Ascencao, S Chlopicki… - Biochemical …, 2024 - Elsevier
The mammalian gasotransmitter hydrogen sulfide (H 2 S) is produced by enzymes such as
cystathionine β-synthase (CBS), cystathionine γ-lyase (CSE), 3-mercaptopyruvate …
cystathionine β-synthase (CBS), cystathionine γ-lyase (CSE), 3-mercaptopyruvate …
[HTML][HTML] Panax notoginseng saponins improves lipid metabolism and prevents atherosclerosis in mice with steroid-resistant lupus nephritis via the SIRT1/PPARγ …
Z Xu, J Huang, K Shi, Y Lu - The Journal of Steroid Biochemistry and …, 2025 - Elsevier
Steroids serve as the primary medication for treating lupus nephritis (LN), however, steroid-
resistance (SR) occurs sporadically in clinical practice, significantly affecting the therapeutic …
resistance (SR) occurs sporadically in clinical practice, significantly affecting the therapeutic …
Study on the anti-skin aging effect and mechanism of Sijunzi Tang based on network pharmacology and experimental validation
H Ke, X Zhang, S Liang, C Zhou, Y Hu, Q Huang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Si Jun Zi Tang (SJZT) is a famous traditional
Chinese medicine formula composing of 4 herbal medicines (Ginseng Radix et Rhizoma …
Chinese medicine formula composing of 4 herbal medicines (Ginseng Radix et Rhizoma …
Impact of Chronic Intermittent Hypoxia on Cognitive Function and Hippocampal Neurons in Mice: A Study of Inflammatory and Oxidative Stress Pathways
K Zhang, D Ma, Y Wu, Z Xu - Nature and Science of Sleep, 2024 - Taylor & Francis
Purpose Chronic intermittent hypoxia (CIH) is considered one of the main
pathophysiological mechanisms of obstructive sleep apnea (OSA). CIH can further lead to …
pathophysiological mechanisms of obstructive sleep apnea (OSA). CIH can further lead to …
Senescence in cardiovascular diseases: Insights into metabolic dysfunction in vascular cells
Y Qu, A Wang, C Long, Q Gao, B Yu - Global Translational …, 2024 - accscience.com
Senescence is an independent risk factor and plays a critical role in altering vascular
structure and functions. Reportedly, senescence accelerates pathological processes and …
structure and functions. Reportedly, senescence accelerates pathological processes and …
[PDF][PDF] The potential role and therapeutic relevance of cellular senescence in skeletal pathophysiology
DDS Ouchi - 2024 - researchgate.net
Biological aging profoundly impairs the homeostasis of the skeletal system. Cellular
senescence, a hallmark of biological aging, plays an instrumental role in bone disease. The …
senescence, a hallmark of biological aging, plays an instrumental role in bone disease. The …