Biochemistry of the respiratory syncytial virus L protein embedding RNA polymerase and capping activities
The human respiratory syncytial virus (RSV) is a negative-sense, single-stranded RNA virus.
It is the major cause of severe acute lower respiratory tract infection in infants, the elderly …
It is the major cause of severe acute lower respiratory tract infection in infants, the elderly …
[HTML][HTML] Structures of the promoter-bound respiratory syncytial virus polymerase
The respiratory syncytial virus (RSV) polymerase is a multifunctional RNA-dependent RNA
polymerase composed of the large (L) protein and the phosphoprotein (P). It transcribes the …
polymerase composed of the large (L) protein and the phosphoprotein (P). It transcribes the …
Structural and mechanistic insights into the inhibition of respiratory syncytial virus polymerase by a non-nucleoside inhibitor
X Yu, P Abeywickrema, B Bonneux, I Behera… - Communications …, 2023 - nature.com
The respiratory syncytial virus polymerase complex, consisting of the polymerase (L) and
phosphoprotein (P), catalyzes nucleotide polymerization, cap addition, and cap methylation …
phosphoprotein (P), catalyzes nucleotide polymerization, cap addition, and cap methylation …
Polysaccharides from Platycodonis Radix ameliorated respiratory syncytial virus-induced epithelial cell apoptosis and inflammation through activation of miR-181a …
JJ Li, ML Liu, JN Lv, RL Chen, K Ding, JQ He - International …, 2022 - Elsevier
Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis in young children, but
there are few safe and effective treatments for this disease. Platycodonis Radix is widely …
there are few safe and effective treatments for this disease. Platycodonis Radix is widely …
Comparison of RNA synthesis initiation properties of non-segmented negative strand RNA virus polymerases
It is generally thought that the promoters of non-segmented, negative strand RNA viruses
(nsNSVs) direct the polymerase to initiate RNA synthesis exclusively opposite the 3´ …
(nsNSVs) direct the polymerase to initiate RNA synthesis exclusively opposite the 3´ …
Supramolecular Self-Assembled Hydrogel for Antiviral Therapy through Glycyrrhizic Acid-Enhanced Zinc Absorption and Intracellular Accumulation
C Lu, C Chang, Y Zheng, J Ji, L Lin… - … Applied Materials & …, 2024 - ACS Publications
Respiratory syncytial virus (RSV) is a common pathogen that causes respiratory infections in
infants and children worldwide, significantly impacting hospitalization rates in this age …
infants and children worldwide, significantly impacting hospitalization rates in this age …
Analysis of template variations on RNA synthesis by respiratory syncytial virus polymerase
D Cao, I Gooneratne, C Mera, J Vy, M Royal, B Huang… - Viruses, 2022 - mdpi.com
Respiratory syncytial virus (RSV) is a significant threat to infants and elderly individuals
globally. Currently, there are no effective therapies or treatments for RSV infection because …
globally. Currently, there are no effective therapies or treatments for RSV infection because …
Optimal Conditions for In Vitro Assembly of Respiratory Syncytial Virus Nucleocapsid-like Particles
The nucleocapsids (NCs) of the respiratory syncytial virus (RSV) can display multiple
morphologies in vivo, including spherical, asymmetric, and filamentous conformations …
morphologies in vivo, including spherical, asymmetric, and filamentous conformations …
Distinctive features of the respiratory syncytial virus priming loop compared to other non-segmented negative strand RNA viruses
TN Cressey, AM Shareef, VA Kleiner, SL Noton… - PLoS …, 2022 - journals.plos.org
De novo initiation by viral RNA-dependent RNA polymerases often requires a polymerase
priming residue, located within a priming loop, to stabilize the initiating NTPs. Polymerase …
priming residue, located within a priming loop, to stabilize the initiating NTPs. Polymerase …
Bioinformatics Analysis Provides Insight into the Identification of miRNAs as Transcriptional Regulators in Respiratory Syncytial Virus Infection
S Shahzadi, M Hassan, A Kloczkowski - International Work-Conference on …, 2024 - Springer
In children under five, the Respiratory Syncytial Virus (RSV) is a leading global cause of
severe lower respiratory tract infections. Due to medical significance of this problem, the …
severe lower respiratory tract infections. Due to medical significance of this problem, the …