Little is known about the mechanism of coronavirus disease 2019 (COVID-19)-induced
critical illness and death. The host infection mediated by SARS-CoV-2 is mainly relied on …

Increased endothelial permeability, one of the earliest signs of endothelial dysfunction, is
associated with the development of cardiovascular diseases such as hypertension and …

Cardiac lymphatic vessel growth (lymphangiogenesis) and integrity play an essential role in
maintaining tissue fluid balance. Inhibition of lymphatic lymphangiogenesis is involved in …

Background: Angiotensin II plays a vital role in the pathogenesis of acute respiratory distress
syndrome (ARDS). However, its mechanism is not well defined. Angiotensin II upregulates …

Abstract Angiotensin II (Ang II) is reported to be involved in the development of various
cardiovascular diseases by disrupting microvessel permeability, however, the underlying …

Lung infection is one of the most common infections in diabetes mellitus and is
characterized by increased pulmonary microvascular endothelial permeability. Local …

Background: Hypoxia induced injury of pulmonary microvascular endothelial barrier is
closely related to the pathogenesis of acute lung injury after lung transplantation. VE …

Background Kawasaki disease (KD) is an acute, self-limited febrile illness of unknown
cause. And it predominantly affects children< 5 years and the main complication is coronary …

Aim: Aortic aneurysm rupture is a significant cause of premature mortality worldwide.
Accordingly, rodent models have been utilised to identify targets and test associated …

Our previous study found that Ang II-associated pulmonary microvascular endothelial cell
apoptosis and skeletal remodeling are the main mechanisms leading to the impaired …