Genomes of diverse origins are continuously shed into human body fluids in the form of
fragmented cell-free DNA (cfDNA). These molecules maintain the genetic and epigenetic …

Objectives The neurofilament light chain (NfL) has emerged as a versatile biomarker for
CNS-diseases and is approaching clinical use. The observed changes in NfL levels are …

Objectives Serum tryptase is a biomarker of mast cell activation. Among others, it is used in
the diagnosis of anaphylaxis where a significant increase during the acute phase supports …

Objectives Serum glial fibrillary acidic protein (GFAP) is an emerging biomarker for
intracerebral diseases and is approved for clinical use in traumatic brain injury. GFAP is also …

BACKGROUND Hypertensive disorders of pregnancy contribute to maternal and offspring
morbidity and mortality. Studies suggest that a lower early pregnancy fetal fraction is …

Objectives Plasma uracil is a new biomarker to assess the activity of dihydropyrimidine
dehydrogenase before cancer treatment with fluoropyrimidine drugs. Knowledge on the …

Introduction: Ovarian cancer (OC) remains the major killer in gynecological oncology. In
Denmark, the 5-year survival rate is around 30%, which is primarily caused by advanced …

A most sincere thanks to my main supervisor Karina Dahl Steffensen for always believing in
me, for inspirational (academic) guidance and discussions; to my supervisor Marianne …