Population stratification (PS) is a primary consideration in studies of genetic determinants of
human traits. Failure to control for PS may lead to confounding, causing a study to fail for …

The underrepresentation of non-Europeans in human genetic studies so far has limited the
diversity of individuals in genomic datasets and led to reduced medical relevance for a large …

Home to a culturally heterogeneous population, India is also a melting pot of genetic
diversity. The population architecture characterized by multiple endogamous groups with …

The origin of Tibetans remains one of the most contentious puzzles in history, anthropology,
and genetics. Analyses of deeply sequenced (30×–60×) genomes of 38 Tibetan highlanders …

Underrepresentation of Asian genomes has hindered population and medical genetics
research on Asians, leading to population disparities in precision medicine. By whole …

The benefits of large-scale genetic studies for healthcare of the populations studied are well
documented, but these genetic studies have traditionally ignored people from some parts of …

Type 2 diabetes (T2D) is one of the major metabolic disorders in humans caused by
hyperglycemia and insulin resistance syndrome. Although significant genetic effects on T2D …

Siberia and Northwestern Russia are home to over 40 culturally and linguistically diverse
indigenous ethnic groups, yet genetic variation and histories of peoples from this region are …

Despite the tremendous growth of the DNA sequencing data in the last decade, our
understanding of the human genome is still in its infancy. To understand the implications of …

Summary Southern East Asia is the dispersal center regarding the prehistoric settlement and
migrations of modern humans in Asia-Pacific regions. However, the settlement pattern and …