Lipopolysaccharide-induced neuroinflammation as a bridge to understand neurodegeneration
CRA Batista, GF Gomes, E Candelario-Jalil… - International journal of …, 2019 - mdpi.com
A large body of experimental evidence suggests that neuroinflammation is a key
pathological event triggering and perpetuating the neurodegenerative process associated …
pathological event triggering and perpetuating the neurodegenerative process associated …
Parkinson's disease: biomarkers, treatment, and risk factors
FN Emamzadeh, A Surguchov - Frontiers in neuroscience, 2018 - frontiersin.org
Parkinson's disease (PD) is a progressive neurodegenerative disorder caused mainly by
lack of dopamine in the brain. Dopamine is a neurotransmitter involved in movement …
lack of dopamine in the brain. Dopamine is a neurotransmitter involved in movement …
The genetics of Parkinson disease
H Deng, P Wang, J Jankovic - Ageing research reviews, 2018 - Elsevier
About 15% of patients with Parkinson disease (PD) have family history and 5–10% have a
monogenic form of the disease with Mendelian inheritance. To date, at least 23 loci and 19 …
monogenic form of the disease with Mendelian inheritance. To date, at least 23 loci and 19 …
[HTML][HTML] Exploring the journey of emodin as a potential neuroprotective agent: novel therapeutic insights with molecular mechanism of action
Emodin is an anthraquinone derivative found in the roots and bark of a variety of plants,
molds, and lichens. Emodin has been used as a traditional medication for more than 2000 …
molds, and lichens. Emodin has been used as a traditional medication for more than 2000 …
Metabolic control of cell death
Background For several decades, intermediate metabolism and signal transduction have
been considered two independent entities. On one side stood the catabolic and anabolic …
been considered two independent entities. On one side stood the catabolic and anabolic …
Mitochondrial dysfunction in Parkinson's disease: from mechanistic insights to therapy
XY Gao, T Yang, Y Gu, XH Sun - Frontiers in aging neuroscience, 2022 - frontiersin.org
Parkinson's disease (PD) is one of the most common neurodegenerative movement
disorders worldwide. There are currently no cures or preventative treatments for PD …
disorders worldwide. There are currently no cures or preventative treatments for PD …
Pharmacological modulation of Nrf2/HO-1 signaling pathway as a therapeutic target of Parkinson's disease
Y Wang, L Gao, J Chen, Q Li, L Huo, Y Wang… - Frontiers in …, 2021 - frontiersin.org
Parkinson's disease (PD) is a complex neurodegenerative disorder featuring both motor and
nonmotor symptoms associated with a progressive loss of dopaminergic neurons in the …
nonmotor symptoms associated with a progressive loss of dopaminergic neurons in the …
N omenclature of genetic movement disorders: R ecommendations of the international P arkinson and movement disorder society task force
C Marras, A Lang, BP van de Warrenburg… - Movement …, 2016 - Wiley Online Library
The system of assigning locus symbols to specify chromosomal regions that are associated
with a familial disorder has a number of problems when used as a reference list of …
with a familial disorder has a number of problems when used as a reference list of …
Clinical approach to Parkinson's disease: features, diagnosis, and principles of management
Parkinson's disease (PD) is one of the most common neurodegenerative disorders. The
condition causes a heavy burden both on those affected, as well as their families. Accurate …
condition causes a heavy burden both on those affected, as well as their families. Accurate …
The new mutation, E46K, of α‐synuclein causes parkinson and Lewy body dementia
JJ Zarranz, J Alegre… - Annals of Neurology …, 2004 - Wiley Online Library
Familial parkinsonism and dementia with cortical and subcortical Lewy bodies is
uncommon, and no genetic defect has been reported in the previously described sibships …
uncommon, and no genetic defect has been reported in the previously described sibships …