Mass spectrometric imaging for biomedical tissue analysis

K Chughtai, RMA Heeren - Chemical reviews, 2010 - ACS Publications
A mass spectrometer is described as the smallest weighing scale ever used in the world. 1
Mass spectrometry (MS) is a unique technique that has an interdisciplinary nature, which …

Mass spectrometry imaging for clinical research–latest developments, applications, and current limitations

PM Vaysse, RMA Heeren, T Porta, B Balluff - Analyst, 2017 - pubs.rsc.org
Mass spectrometry is being used in many clinical research areas ranging from toxicology to
personalized medicine. Of all the mass spectrometry techniques, mass spectrometry …

Fully automated liquid extraction‐based surface sampling and ionization using a chip‐based robotic nanoelectrospray platform

V Kertesz, GJ Van Berkel - Journal of mass spectrometry, 2010 - Wiley Online Library
A fully automated liquid extraction‐based surface sampling device utilizing an Advion
NanoMate chip‐based infusion nanoelectrospray ionization system is reported. Analyses …

Advancing the sensitivity of selected reaction monitoring‐based targeted quantitative proteomics

T Shi, D Su, T Liu, K Tang, DG Camp, WJ Qian… - …, 2012 - Wiley Online Library
Selected reaction monitoring (SRM)–also known as multiple reaction monitoring (MRM)–has
emerged as a promising high‐throughput targeted protein quantification technology for …

Quantification of low molecular weight compounds by MALDI imaging mass spectrometry–A tutorial review

I Rzagalinski, DA Volmer - Biochimica et Biophysica Acta (BBA)-Proteins …, 2017 - Elsevier
Matrix-assisted laser desorption/ionization (MALDI)-mass spectrometry imaging (MSI)
permits label-free in situ analysis of chemical compounds directly from the surface of two …

Quantitative MALDI tandem mass spectrometric imaging of cocaine from brain tissue with a deuterated internal standard

DA Pirman, RF Reich, A Kiss, RMA Heeren… - Analytical …, 2013 - ACS Publications
Mass spectrometric imaging (MSI) is an analytical technique used to determine the
distribution of individual analytes within a given sample. A wide array of analytes and …

Recent methodological advances in MALDI mass spectrometry

K Dreisewerd - Analytical and bioanalytical chemistry, 2014 - Springer
Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is widely used
for characterization of large, thermally labile biomolecules. Advantages of this analytical …

[图书][B] High performance liquid chromatography in phytochemical analysis

M Waksmundzka-Hajnos, J Sherma - 2010 - books.google.com
This volume is the first book to give a complete description of the techniques, materials, and
instrumentation of column HPLC and its application to essentially all primary and secondary …

Biomedical application of MALDI mass spectrometry for small‐molecule analysis

JJA van Kampen, PC Burgers… - Mass spectrometry …, 2011 - Wiley Online Library
Matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry (MS) is an emerging
analytical tool for the analysis of molecules with molar masses below 1,000 Da; that is, small …

Mass spectrometric imaging of small molecules

A Svatoš - Trends in biotechnology, 2010 - cell.com
Small molecules are defined as low molecular weight organic compounds (typically<
1000Da), which could be either natural or artificial. Because established imaging methods …