Alginate and its application to tissue engineering

DR Sahoo, T Biswal - SN Applied Sciences, 2021 - Springer
Alginate is a polysaccharide of natural origin, which shows outstanding properties of
biocompatibility, gel forming ability, non-toxicity, biodegradability and easy to process. Due …

Targeting early atherosclerosis: a focus on oxidative stress and inflammation

P Marchio, S Guerra-Ojeda, JM Vila… - Oxidative medicine …, 2019 - Wiley Online Library
Atherosclerosis is a chronic vascular inflammatory disease associated to oxidative stress
and endothelial dysfunction. Oxidation of low‐density lipoprotein (LDL) cholesterol is one of …

LOX‐1, OxLDL, and atherosclerosis

A Pirillo, GD Norata, AL Catapano - Mediators of inflammation, 2013 - Wiley Online Library
Oxidized low‐density lipoprotein (OxLDL) contributes to the atherosclerotic plaque formation
and progression by several mechanisms, including the induction of endothelial cell …

The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease

Y Döring, L Pawig, C Weber, H Noels - Frontiers in physiology, 2014 - frontiersin.org
The chemokine receptor CXCR4 and its ligand CXCL12 play an important homeostatic
function by mediating the homing of progenitor cells in the bone marrow and regulating their …

[HTML][HTML] Sodium-glucose co-transporter2 expression and inflammatory activity in diabetic atherosclerotic plaques: Effects of sodium-glucose co-transporter2 inhibitor …

N D'Onofrio, C Sardu, MC Trotta, L Scisciola… - Molecular …, 2021 - Elsevier
Objective We evaluated sodium-glucose co-transporter2 (SGLT2) expression and the effect
of SGLT2 inhibitor (SGLT2i) therapies on carotid plaques of asymptomatic diabetic and non …

Biotherapeutic-loaded injectable hydrogels as a synergistic strategy to support myocardial repair after myocardial infarction

Z Zheng, Y Tan, Y Li, Y Liu, G Yi, CY Yu… - Journal of Controlled …, 2021 - Elsevier
Myocardial infarction (MI) has been considered as the leading cause of cardiovascular-
related deaths worldwide. Although traditional therapeutic agents including various …

Mitochondrial reactive oxygen species mediate lysophosphatidylcholine-induced endothelial cell activation

X Li, P Fang, Y Li, YM Kuo, AJ Andrews… - … , and vascular biology, 2016 - Am Heart Assoc
Objective—Hyperlipidemia-induced endothelial cell (EC) activation is considered as an
initial event responsible for monocyte recruitment in atherogenesis. However, it remains …

Effect of endothelial progenitor cell-derived extracellular vesicles on endothelial cell ferroptosis and atherosclerotic vascular endothelial injury

L Li, H Wang, J Zhang, X Chen, Z Zhang, Q Li - Cell death discovery, 2021 - nature.com
Atherosclerosis (AS) is a chronic inflammatory disorder characterized by endothelial
dysfunction. Endothelial progenitor cells (EPCs) can overcome endothelial dysfunction and …

Sirtuin 6 expression and inflammatory activity in diabetic atherosclerotic plaques: effects of incretin treatment

ML Balestrieri, MR Rizzo, M Barbieri, P Paolisso… - Diabetes, 2015 - Am Diabetes Assoc
The role of sirtuin 6 (SIRT6) in atherosclerotic progression of diabetic patients is unknown.
We evaluated SIRT6 expression and the effect of incretin-based therapies in carotid plaques …

Regenerative medicine for the treatment of ischemic heart disease; status and future perspectives

B Arjmand, M Abedi, M Arabi… - Frontiers in Cell and …, 2021 - frontiersin.org
Cardiovascular disease is now the leading cause of adult death in the world. According to
new estimates from the World Health Organization, myocardial infarction (MI) is responsible …