[HTML][HTML] Battling chemoresistance in cancer: root causes and strategies to uproot them

A Ramos, S Sadeghi, H Tabatabaeian - International journal of molecular …, 2021 - mdpi.com
With nearly 10 million deaths, cancer is the leading cause of mortality worldwide. Along with
major key parameters that control cancer treatment management, such as diagnosis …

Phytochemicals in cancer cell chemosensitization: Current knowledge and future perspectives

E Khatoon, K Banik, C Harsha, BL Sailo… - Seminars in Cancer …, 2022 - Elsevier
Despite significant advancements made in the treatment of cancer during the past several
decades, it remains one of the leading causes of death worldwide killing approximately 9.6 …

Kaempferol can reverse the 5-Fu resistance of colorectal cancer cells by inhibiting PKM2-mediated glycolysis

H Wu, J Du, C Li, H Li, H Guo, Z Li - International Journal of Molecular …, 2022 - mdpi.com
Resistance to 5-Fluorouracil (5-Fu) chemotherapy is the main cause of treatment failure in
the cure of colon cancer. Therefore, there is an urgent need to explore a safe and effective …

Polyphenols in food: Cancer prevention and apoptosis induction

A Sharma, M Kaur, JK Katnoria… - Current medicinal …, 2018 - ingentaconnect.com
Polyphenols are a group of water-soluble organic compounds, mainly of natural origin. The
compounds having about 5-7 aromatic rings and more than 12 phenolic hydroxyl groups are …

Encapsulation and controlled release of resveratrol within functionalized mesoporous silica nanoparticles for prostate cancer therapy

Z Chaudhary, S Subramaniam, GM Khan… - … in bioengineering and …, 2019 - frontiersin.org
Resveratrol (RES) is a naturally existing polyphenol which exhibits anti-oxidant, anti-
inflammatory, and anti-cancer properties. In recent years, RES has attracted attention for its …

The Phenolic compound Kaempferol overcomes 5-fluorouracil resistance in human resistant LS174 colon cancer cells

I Riahi-Chebbi, S Souid, H Othman, M Haoues… - Scientific Reports, 2019 - nature.com
Resistance to 5-Fluorouracil chemotherapy is a major cause of therapeutic failure in colon
cancer cure. Development of combined therapies constitutes an effective strategy to inhibit …

Anticancer potential of flavonoids: an overview with an emphasis on tangeretin

FCF de Luna, WAS Ferreira, SMM Casseb… - Pharmaceuticals, 2023 - mdpi.com
Natural compounds with pharmacological activity, flavonoids have been the subject of an
exponential increase in studies in the field of scientific research focused on therapeutic …

[HTML][HTML] Phytochemical based nanomedicine: a panacea for cancer treatment, present status and future prospective

P Mohapatra, P Singh, D Singh, S Sahoo, SK Sahoo - OpenNano, 2022 - Elsevier
Cancer is one of the leading causes of mortality worldwide. Currently available anticancer
therapeutic strategies are not able to improve the survival rate of patients over the past few …

Alleviation of multidrug resistance by flavonoid and non-flavonoid compounds in breast, lung, colorectal and prostate cancer

T Costea, OC Vlad, LC Miclea, C Ganea… - International journal of …, 2020 - mdpi.com
The aim of the manuscript is to discuss the influence of plant polyphenols in overcoming
multidrug resistance in four types of solid cancers (breast, colorectal, lung and prostate …

Herbal therapies for cancer treatment: A review of phytotherapeutic efficacy

A Jenča, DK Mills, H Ghasemi, E Saberian… - … : Targets and Therapy, 2024 - Taylor & Francis
Natural products have proven to be promising anti-cancer agents due to their diverse
chemical structures and bioactivity. This review examines their central role in cancer …