The cause of chronic rhinosinusitis (CRS) remains unclear. Study of the genetic
susceptibility to CRS might be a valuable strategy to understand the pathogenesis of this …

CRS has a broad spectrum of associations ranging from genetics to comorbid diseases and
environmental factors. These predisposing factors may provide valuable information for …

Background Chronic rhinosinusitis (CRS) is a highly prevalent inflammatory condition, with
significant effects on morbidity and quality of life, yet little is known about its pathogenesis …

Background Chronic rhinosinusitis (CRS) with nasal polyps is a common chronic condition.
The exact cause of nasal polyps remains unknown. Recently, we made the novel …

Individual genetic background together with environmental effects are thought to be behind
many human complex diseases. A number of genetic variants, mainly single nucleotide …

Chronic rhinosinusitis (CRS) is defined in adults as persistent symptoms of sinonasal
inflammation for 12 or more weeks with confirmatory objective findings on nasal endoscopy …

Aspirin intolerance is a severe and rare asthmatic endotype, with prevalence rates of 10% in
the adult asthmatic population and up to 25% in patients with severe, persistent asthma. 1–4 …

Chronic polyposis rhinosinusitis (CPRS) is an important medical and social problem due to
its prevalence, combination with other diseases (bronchial asthma, cystic fibrosis) …

Chronic rhinosinusitis (CRS) is a significant public health problem. Bacterial colonization
and impaired mucociliary clearance play a significant role in the inflammatory process …

Rhinosinusitis (RS) is an inflammatory process of the nasal mucosa, and according to the
evolution of signs and symptoms, it is classified as acute (ARS;< 12 weeks) or chronic …